ROCK-IN-1 |
カタログ番号GC31952 |
ROCK-IN-1 は ROCK の強力な阻害剤であり、ROCK2 の IC50 は 1.2 nM です。
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Cas No.: 934387-35-6
Sample solution is provided at 25 µL, 10mM.
ROCK-IN-1 is a potent inhibitor of ROCK, with an IC50 of 1.2 nM for ROCK2.
ROCK-IN-1 shows potent cellular efficacy, with an EC50 of 200 nM[1].
[1]. Boland S, et al. 3-[2-(Aminomethyl)-5-[(pyridin-4-yl)carbamoyl]phenyl] benzoates as soft ROCK inhibitors. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6442-6.
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Average Rating: 5
(Based on Reviews and 27 reference(s) in Google Scholar.)Review for ROCK-IN-1
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