UNC0379 |
| カタログ番号GC16741 |
UNC0379 は、リジンメチルトランスフェラーゼ SETD8 (KMT5A) の選択的基質競合阻害剤であり、IC50 は 7.3 μM、KD 値は 18.3 μM です。
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Cas No.: 1620401-82-2
Sample solution is provided at 25 µL, 10mM.
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UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 (KMT5A) with an IC50 of 7.3 μM; selective over 15 other methyltransferases[1].
References:
[1]. Ma A, et al. Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8. J Med Chem. 2014 Aug 14;57(15):6822-33.
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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