K67 |
| Catalog No.GC66004 |
K67 specifically inhibits the interaction between Keap1 and S349-phosphorylated p62. K67 prevents p-p62 from blocking the binding of Keap1 and Nrf2. K67 effectively inhibits the proliferation of HCC cultures with high cellular S351-phosphorylated p62 by restoring the ubiquitination and degradation of Nrf2 driven by Keap1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2046250-48-8
Sample solution is provided at 25 µL, 10mM.
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K67 specifically inhibits the interaction between Keap1 and S349-phosphorylated p62. K67 prevents p-p62 from blocking the binding of Keap1 and Nrf2. K67 effectively inhibits the proliferation of HCC cultures with high cellular S351-phosphorylated p62 by restoring the ubiquitination and degradation of Nrf2 driven by Keap1[1].
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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