>>Signaling Pathways>> Cardiovascular>> Thrombosis>>(±)-Warfarin-d5

(±)-Warfarin-d5

Catalog No.GC40229

(±)-Warfarin-d5 is intended for use as an internal standard for the quantification of warfarin by GC- or LC-MS.

Products are for research use only. Not for human use. We do not sell to patients.

(±)-Warfarin-d5 Chemical Structure

Cas No.: 75472-93-4

Size 가격 재고 수량
500μg
US$265.00
재고 있음
1mg
US$425.00
재고 있음

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고객 리뷰

Based on customer reviews.

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Sample solution is provided at 25 µL, 10mM.

Product Documents

Quality Control & SDS

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Background

(±)-Warfarin-d5 is intended for use as an internal standard for the quantification of warfarin by GC- or LC-MS. (±)-Warfarin is a vitamin K antagonist, a coumarin derivative, and a racemic mixture of (+)-warfarin and (-)-warfarin . It is an anticoagulant that interferes with the interconversion of vitamin K and vitamin K epoxide and the role of vitamin K in carboxylation of several clotting cascade proteins, inhibiting the initiation of clotting. Formulations containing warfarin have been used to treat and prevent blood clots in atrial fibrillation, heart valve replacement, venous thrombosis, and pulmonary embolism.

Chemical Properties

Cas No. 75472-93-4 SDF
Canonical SMILES O=C1OC2=CC=CC=C2C(O)=C1C(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])CC(C)=O
Formula C19H11D5O4 M.Wt 313.4
Solubility DMF: 25 mg/ml,DMSO: 25 mg/ml,Ethanol: 5 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

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1 mg 5 mg 10 mg
1 mM 3.1908 mL 15.9541 mL 31.9081 mL
5 mM 0.6382 mL 3.1908 mL 6.3816 mL
10 mM 0.3191 mL 1.5954 mL 3.1908 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

리뷰

Review for (±)-Warfarin-d5

Average Rating: 5 ★★★★★ (Based on Reviews and 24 reference(s) in Google Scholar.)

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