GLPBio

FGFR

FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.

Products Related to FGFR(109)

  • GC73852 structure
    GC73852Infigratinib-Boc
    CAS: 2504949-83-9
    Purity: >98.00%

    Infigratinib-Boc는 Boc (t-Butyloxy carbonyl) 그룹을 포함하는 Infigratinib의 유도체이다.

  • GC73947 structure
    GC73947CEP-11981
    CAS: 856691-93-5
    Purity: >99.00%

    CEP-11981 (ESK981; BOL 303213X) 는 TIE2, VEGFR1-3 및 FGFR1을 표적으로 할 수있는 경구 활성 타이로신 효소 억제제 (TKI) 로 잠재적 인 항종양 및 항혈관 생성 작용을 가지고 있습니다.

  • GC74046 structure
    GC74046BR-cpd7
    Purity: >98.00%

    BR-cpd7는 DC50이 10 nM인 섬유아세포 성장인자 수용체 FGFR1/2의 PROTAC 분해제이다.

  • GC74365 structure
    GC74365VSPPLTLGQLLS
    CAS: 1206896-24-3
    Purity: >98.00%

    VSPPLTLGQLLS 는 작은 펩타이드 FGFR3 억제제, 펩타이드 P3, FGFR3 인산화 억제.

  • GC79483 structure
    GC79483MD-3-A45
    CAS: 2314337-87-4
    Purity: >98.00%

    MD-3-A45 is an inhibitor of fibroblast growth factor 23 ( FGF-23 ).

  • GC81314 structure
    GC81314OM-RCA-01
    Purity: >99.00%

    OM-RCA-01 is an anti- FGFR1 monoclonal antibody with a K d of 1.59 nM for human FGFR1.

  • GC81319 structure
    GC813192,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose
    CAS: 150302-84-4
    Purity: >98%

    2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica.

  • GC81324 structure
    GC81324FGF7p
    CAS: 2758194-43-1
    Purity: >99.00%

    FGF7p is a small molecule peptide and a potential bladder protector.

  • GC81325 structure
    GC81325VEGFR2-IN-84
    CAS: 861877-12-5
    Purity: >98%

    VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold.

  • GC81329 structure
    GC81329TCB-32 hydrochloride
    CAS: 169764-95-8
    Purity: >97.50%

    TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM.

  • GC91419 structure
    GC91419CYY292
    CAS: 2644673-04-9
    Purity: >98.00%

    CYY292는 PDGFRα, PDGFRβ, FGFR1,-2 및 -3의 억제제입니다. (각각 IC50s = 5.35, 4.6, 28, 28 및 78 nM).

  • GN10527 structure
    GN10527Formononetin
    CAS: 485-72-3
    Purity: >99.50%

    Formononetin은 효과적인 FGFR2 억제제로 IC 50 가 4.3μM이다. Formononetin은 혈관 형성과 종양 성장을 강력하게 억제한다.

  • GN10540 structure
    GN10540Fumalic acid
    CAS: 1135-24-6
    Purity: >99.00%

    A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.