Cyclooxygenase

Prostaglandin F2β (PGF2β) (tromethamine salt) is a derivative of PGF2β with increased water solubility.

PGI3 is synthesized from EPA by COX and PGI synthase.

Prostaglandin E2 activates four distinct G protein-coupled receptors, EP1-4.

S-5751 is an antagonist of the prostaglandin D2 (PGD2) receptor DP1 (Ki = 1.6 nM) that shows at least 20-fold selectivity over receptors for thromboxane and prostacyclin, as well as the PGE2 receptor EP2.

Analogs of prostaglandin F2α (PGF2α), which act primarily at the FP receptor, have been approved for the treatment of glaucoma.

Taprostene (free acid) (CG-4203) is a synthetic, chemically stable analogue of Prostacyclin (PGI2).

TBS-Corey lactone aldehyde is a versatile, hydroxyl-protected intermediate for the synthesis of prostaglandins and prostaglandin analogs.

Metabolism of 12(R)-HETE in corneal tissue produces predominantly the compound resulting from the loss of four carbon atoms through β-oxidation from C-1.

Prostaglandin D2 is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis.

tetranor-PGEM is a metabolite of prostaglandin E2 (PEG2) as a biomarker of inflammation and cancer including advanced colorectal neoplasia, ovarian cancer, prostate cancer and so on.

tetranor-PGFM is the major urinary metabolite of PGF2α.

Prostaglandin E2 evokes distinct responses through four different 'E prostanoid' (EP) receptors.

Thielavin A is a fungal metabolite originally isolated from T.

Thielavin B is a fungal metabolite that contains O-substituted salicylic acid.

Dihomo-g-linolenic acid (DGLA) is one of the 20-carbon fatty acids that can be metabolized to prostaglandins and thromboxanes (TXs) by cyclooxygenases 1 and 2 (COX-1/COX-2).

Thromboxane A2 (TXA2) is produced from arachidonic acid by many cells and causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle.

U-46619 is a stable analog of the endoperoxide PGH2, and a TP receptor agonist.

U-51605 is a stable analog of the endoperoxide prostaglandin H2 (PGH2).

Unoprostone isopropyl ester (Unoprostone isopropyl ester), an analogue of a prostaglandin metabolite, is a potent large conductance Ca2+-activated K+ (BK) channels activator.

Vedaprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used in veterinary medicine to combat pain, inflammation, and fever associated with acute and chronic musculoskeletal disorders in horses and dogs.

Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma.

(+)-5-trans Cloprostenol isopropyl ester is a more lipid soluble form of (+)-5-trans cloprostenol , which is a less active form of the synthetic prostaglandin F2α (PGF2α) derivative cloprostenol .

(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α).

(+)-Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α).