Leukotrienes

20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils.

18-carboxy dinor Leukotriene B4 (18-carboxy dinor LTB4) is a β-oxidation metabolite of LTB4.

20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils.

Dual cyclooxygenase-2 (COX-2)/5-lipoxygenase (5-LO) inhibitors are potential therapeutic agents for inflammatory diseases and for prostate cancer.

Essential fatty acid deficiency symptoms include immune system depression and a general state of inflammatory inhibition.

Diflapolin is a dual inhibitor of 5-lipoxygenase-activating protein (FLAP) and soluble epoxide hydrolase (sEH).

LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL.

The effects of Leukotriene B4 (LTB4) are mediated by two known receptors, BLT1 and BLT2.

Leukotriene C4 (LTC4) is the parent cysteinyl-leukotriene produced by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4.

Leukotriene D4 (LTD4) is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) produced by the metabolism of LTC4 by γ-glutamyl transpeptidase.

Leukotriene E4 (LTE4) is produced by the action of a dipeptidase on LTD4 leaving only the cysteinyl group still attached to the fatty acid backbone.

N-acetyl LTE4 is the major inactive metabolite of LTE4 found in bile.

Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione to LTA4.

Proline-glycine-proline (PGP) is a tripeptide molecule and an established biomarker for chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF).

A neuropeptide with diverse biological activities

Terbutaline is a novel selective β2-adrenergic receptor agonist.

A fungal metabolite

A neuropeptide with diverse biological activities

A neuropeptide with diverse biological activities

A neuropeptide with diverse biological activities

An inhibitor of 5-LO

An internal standard for the quantification of loratadine

An internal standard for the quantification of zileuton

An internal standard for the quantification of olsalazine