GLPBio

Monoamine transporter

Monoamine transporters are a family of plasma membrane transporter that regulates the reuptake of neurotransmitters into nerve terminals. It divided into DAT (dopamine transporter), NET (norepinephrine transporter) and SERT (serotonin transporter).

Products Related to Monoamine transporter(16)

  • GC14792 structure
    GC14792Reserpine hydrochloride
    CAS: 16994-56-2
    Purity: >99.50%

    Blocker of VMAT

  • GC13672 structure
    GC13672Tetrabenazine
    CAS: 58-46-8
    Purity: >99.50%

    Tetrabenazine is a brain-penetrant and orally active synaptic vesicular monoamine transporter (VMAT2)-selective ligand with K i 2.34nM.

  • GC19370 structure
    GC19370Valbenazine
    CAS: 1025504-45-3
    Purity: >99.00%

    Valbenazine is a prodrug of the (+)-α isomer of tetrabenazine for tardive syndrome therapy, and inhibits VMAT2 function.

  • GC26029 structure
    GC26029Valbenazine tosylate
    CAS: 1639208-54-0
    Purity: >98%

    Valbenazine tosylate (NBI-98854) is the tosylate salt of valbenazine, a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no significant binding to VAMT1(Ki<10 μM).

  • GC30994 structure
    GC30994Vanilpyruvic acid (Vanylpyruvic acid)
    CAS: 1081-71-6
    Purity: >98.00%

    Vanilpyruvic acid (Vanylpyruvic acid) is a catecholamine metabolite and precursor to vanillactic acid.

  • GC31060 structure
    GC31060Radafaxine hydrochloride (GW-353162A)
    CAS: 106083-71-0
    Purity: >99.50%

    Radafaxine hydrochloride (GW-353162A) (GW-353162A) is a DAT (dopamine transporter) and NET(norepinephrine transporter) transporters inhibitor, and nAChR family modulator.

  • GC36705 structure
    GC36705NBI-98782
    CAS: 85081-18-1
    Purity: >98.50%

    NBI-98782 is a potent and selective vesicular monoamine transporter 2 (VMAT2) inhibitor with a K i value of 3nM.

  • GC37768 structure
    GC37768Tetrabenazine Racemate
    CAS: 718635-93-9
    Purity: >98.00%

    Tetrabenazine Racemate (Ro 1-9569 Racemate) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2).

  • GC37820 structure
    GC37820Trans (2,3)-Dihydrotetrabenazine
    CAS: 171598-74-6
    Purity: >98%

    Trans (2,3)-Dihydrotetrabenazine ((2R,3R,11bR)-rel-Dihydrotetrabenazine), a metabolite of Tetrabenazine, shows remarkable inhibition activity on vesicular monoamine transporter (VMAT2).

  • GC40180 structure
    GC40180Tetrabenazine-d6
    CAS: 1392826-25-3
    Purity: >99.00%

    Tetrabenazine-d6 is intended for use as an internal standard for the quantification of tetrabenazine by GC- or LC-MS.

  • GC50649 structure
    GC50649FFN 200 dihydrochloride
    CAS: 2080306-27-8
    Purity: >98.00%
  • GC69565 structure
    GC69565Nisoxetine
    CAS: 53179-07-0
    Purity: >98.00%

    Nisoxetine is an effective and selective norepinephrine transporter (NET) inhibitor with a Kd value of 0.76 nM. It is an antidepressant agent and local anesthetic that can block voltage-gated sodium channels.

  • GC70443 structure
    GC70443GZ-793A
    CAS: 1356447-90-9
    Purity: >99.00%

    GZ-793A is an orally active and selective vesicular monoamine transporter-2 (VMAT2) inhibitor, with an Ki of 0.029 µM.

  • GC73217 structure
    GC73217FFN246
    CAS: 2210244-83-8
    Purity: >99.00%

    FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm.

  • GC79493 structure
    GC79493F3288-0031
    CAS: 926493-93-8
    Purity: >98%

    F3288-0031 is a brain-penetrant norepinephrine transporter ( NET ) allosteric inhibitor with inhibitory rates of 73.5% at 20 μM.

  • GN10779 structure
    GN10779Reserpine
    CAS: 50-55-5
    Purity: >98.50%