Ophthalmology

Endogenous agonist for the GPR55 and CB1 receptors

Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases u-calpain (calpain-1; IC50 = 7.5 nM) and m-calpain (calpain-2; IC50 = 78 nM).

Oxyphenonium is an antagonist of muscarinic acetylcholine receptors that binds to muscarinic receptors on isolated guinea pig atria and ileum (Kds = 0.11 and 0.17 nM, respectively).

Prostaglandin F2α methyl ester (PGF2α methyl ester) is an analog of PGF2α in which the C-1 carboxyl group has been esterified as the methyl ester.

Tafluprost ethyl amide is derived from 17-phenyl trinor Prostaglandin F2α(17-phenyl trinor PGF2α).

A metabolite of meloxicam

11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.

Echothiophate (iodide) is a potent hBChE (human butyrylcholinesterase) inhibitor.

11-cis Retinal is a chromophore that binds to opsin in the mammalian visual system as an inverse agonist forming the inactive conformation of rhodopsin.

Prostaglandin F2α alcohol (PGF2α-OH) is an analog of PGF2α in which the C-1 carboxyl group has been reduced to a primary alcohol.

ML221 is a potent apelin (APJ) functional antagonist

Methylprednisolone acetate, a prednisolone derivative, is a corticosteroid?hormone.

Kynurenic acid-d5 is the deuterium labeled Kynurenic acid.

An acetate form of dexamethasone

Cholesteryl lignocerate is a cholesterol ester that has been found in human meibum.

Cholesteryl erucate is a cholesterol ester.

Brimonidine-d4 is intended for use as an internal standard for the quantification of brimonidine by GC- or LC-MS.

Ibuprofen carboxylic acid is a major metabolite of ibuprofen.

17-phenyl trinor Prostaglandin F2α methyl ester is a prodrug of Bimatoprost.

Prostaglandin F2α alcohol methyl ether (PGF2α-OMe) is an analog of PGF2α in which the C-1 carboxyl group has been replaced an O-methyl ether.

7-keto Cholesterol is a major oxysterol associated with vascular disease. It is widely present in atherosclerotic plaques and has a stronger atherogenic effect than cholesterol.

Prostaglandin D3 (PGD3) is produced by the metabolism of EPA via the COX pathway.

Prostaglandin E3 (PGE3) is formed via the cyclooxygenase (COX) metabolism of eicosapentaenoic acid.

Tafluprost (free acid) (AFP-172), an active metabolic form of Tafluprost, is a selective prostanoid FP receptor agonist.