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RADA

Catalog No.GC50535 Copy One-Click Copy Product Info

Orange-red TAMRA-based fluorescent D-amino acid for labeling peptidoglycans in live bacteria

Products are for research use only. Not for human use. We do not sell to patients.

RADA Chemical Structure

Size Price Stock Qty
5mg
$622.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of RADA

Orange-red TAMRA-based fluorescent D-amino acid. Suitable for labeling peptidoglycans in live bacteria. Incorporated into bacterial cell walls during synthesis. Suitable for prolonged exposure due to red-shift photophysical properties. Suitable for dSTORM and reSTORM. Displays good water solubility, photostability and thermostability. Excitation/emission λ ~554/580 nm. This product is supplied as a TFA salt, the stoichiometry of which is batch dependant. Please refer to the Certificate of Analysis to obtain the batch specific Net Product Content,

Hsu et al (2017) Full color palette of fluorescent d-amino acids for in situ labeling of bacterial cell walls. Chem.Sci. 8 6313 PMID:28989665 |García-Heredia et al (2018) Peptidoglycan precursor synthesis along the sidewall of pole-growing mycobacteria. Elife 7 pii: e37243. PMID:30198841 |Fenton et al (2017) Erratum: CozE is a member of the MreCD complex that directs cell elongation in Streptococcus pneumoniae. Nat.Microbiol. 2 17011 PMID:28112724

Chemical Properties of RADA

Cas No. SDF
Canonical SMILES N[C@@H](C(O)=O)CNC(C)=O.C/[N+](C)=C1C=C2OC(C=C(N(C)C)C=C3)=C3C(C4=C(C([O-])=O)C=CC=C4)=C2C=C/1
Formula C28H28N4O6 M.Wt 516.55
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of RADA

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.9359 mL 9.6796 mL 19.3592 mL
5 mM 387.2 μL 1.9359 mL 3.8718 mL
10 mM 193.6 μL 968 μL 1.9359 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of RADA

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Reviews

Review for RADA

Average Rating: 5 ★★★★★ (Based on Reviews and 19 reference(s) in Google Scholar.)

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