Glucocorticoid Receptor

Dazucorilant (CORT113176) is a selective and high affinity non-steroidal glucocorticoid receptor (GR) modulator with a Ki value ＜1 nM in vitro.

AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM).

BI 653048 is a selective and orally active nonsteroidal?glucocorticoid (GC)?agonist with an IC50 value of 55 nM.

ORIC-101 is a highly potent and selective glucocorticoid receptor antagonist, with an EC50 of 5.6 nM.

Budesonide impurity C is an impurity of Budesonide. Budesonide is an inhaled corticosteroid and a glucocorticoid receptor agonist with oral activity.

Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal is a type of glucocorticoid receptor agonist. It can be used for anti-CD40 antibody-drug conjugate (ADC) therapy and in research related to inflammation and immune regulation.

INCB13739 is an orally effective, selective, and tissue-specific inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), with IC50 values of 3.2 nM (for the enzyme) and 1.1 nM (for PBMC). INCB13739 can be used for research on type 2 diabetes (T2DM) and obesity.

Methylprednisolone aceponate (ZK 91588) is a glucocorticoid and anti-inflammatory agent with weak systemic effects.

Exicorilant (CORT 125281) is a selective and oral active glucocorticoid receptor (GR) antagonist, with a Ki value of 7 nM.

C108297 is a selective glucocorticoid receptor (GR) modulator (GR binding Ki 0.7 nM; GR reporter gene functional Ki 0.6 nM).

Beclometasone dipropionate-d10 is the deuterium labeled Beclometasone dipropionate.

HP210 is a selective glucocorticoid receptor modulator (SGRM).

Glucocorticoid receptor modulator 2 (Example 1) is a glucocorticoid receptor modulator, with an IC50 value less than 100 nM.

Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br is an Drug-linker conjugates for ADC that can be used as a reaction reagent for the synthesis of anti-CD40 antibody agent conjugates (ADCs).

GSK866 is a selective glucocorticoid receptor agonist, with an IC50 of 4.6 nM.

(R)-GSK866 is the (R)-enantiomer of GSK866.

Glucocorticoid receptor agonist-4 (Compound Preparation 5) is a glucocorticoid receptor agonist that can be conjugated to TNF-α antibodies for the study of autoimmune and inflammatory diseases.

GA32 (compound 58r) is potent androgen receptor (AR)/glucocorticoid receptor (GR) dual inhibitor with IC50 values of 0.13 μM and 0.83 μM for AR and GR, respectively.

Hydrocortisone -OVA is a conjugate of Hydrocortisone and OVA peptide.

glucocorticoid