Glucocorticoid Receptor

Hydrocortisone phosphate (Hydrocortisone 21-phosphate), a physiological glucocorticoid, and is an orally active steroidal anti-in?ammatory drug (SAID).

OP-3633 is a potent and selective steroidal glucocorticoid receptor (GR) antagonist with an IC50 of 29 nM, with inhibition of GR transcriptional activity.

Prednisolone tebutate is a synthetic glucocorticoid used as an antiinflammatory and immunosuppressant.

Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties.

Dexamethasone palmitate is a highly lipophilic glucocorticoid prodrug. Dexamethasone palmitate exhibits 47-fold lower affinity for the glucocorticoid receptor compared to Dexamethasone.

A synthetic glucocorticoid

Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin.

Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).

Vamorolone (VBP15) is a first-in-class, orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer.

Fluorometholone is a synthetic glucocorticoid that binds to glucocorticoid receptors (IC50 = 1.5 nM; Kd = 2.8 nM in a radioligand binding assay).

Dexamethasone is a corticosteroid compound that has been used as an adjuvant to reduce postoperative pain.

6α-Methylprednisolone 21-hemisuccinate is a synthetic glucocorticoid and widely used as an anti-inflammatory agent.

Amcinonide is a synthetic corticosteroid.

Prednisolone Phosphate (sodium salt) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.

A synthetic corticosteroid

21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione is an intermediate of delta 9,11 steroids synthesis, for example, Vamorolone?

Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid, is an orally active steroidal anti-in?ammatory drug (SAID).

Beclomethasone 17-propionate (Beclomethasone-17-monopropionate), an active metabolite of Beclomethasone dipropionate, is a glucocorticoid receptor (GR) agonist.

Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM extracted from patent WO2017210471A1, compound 41.

Dagrocorat (PF-00251802) hydrochloride is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor.