Glucocorticoid Receptor
Glucocorticoid receptor is a neuroendocrine integration that functions as a major component of endocrine influence - specifically the stress response - upon the brain.
Products for Glucocorticoid Receptor
- Cat.No. Product Name Information
- GC34965 (20S)-Protopanaxatriol An active ginsenoside metabolite
- GC35002 (S)-Mapracorat (S)-Mapracorat is a selective and less active glucocorticoid receptor agonist.
- GC60467 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione is an intermediate of delta 9,11 steroids synthesis, for example, Vamorolone?
- GC63737 21-Desacetyldeflazacort-D5
- GC42587 6α-Methylprednisolone 21-hemisuccinate 6α-Methylprednisolone 21-hemisuccinate is a synthetic glucocorticoid and widely used as an anti-inflammatory agent.
- GC32405 AL 082D06 (D06) AL 082D06 (D06) is a selective, nonsteroidal glucocorticoid receptor (GR) antagonist with Ki of 210 nM.
- GC42782 Amcinonide Amcinonide is a synthetic corticosteroid.
- GC31929 Amebucort Amebucort is a synthetic glucocorticoid corticosteroid, may used for the research of inflammatory disorders.
- GC32585 AZD2906 AZD2906 is a selective glucocorticoid receptor (GR) agonist, increases micronucleated immature erythrocytes in the bone marrow of rats.
- GC64949 AZD5423 AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM).
- GC19051 AZD7594 AZD7594 is a potent selective nonsteroidal glucocorticoid receptor modulator, with an IC50 of 0.9 nM.
- GC31894 AZD9567 AZD9567 (compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM.
- GC33856 Beclometasone (Beclomethasone) Beclometasone (Beclomethasone) (Beclomethasone) is a prototype glucocorticoid receptor agonist.
- GC35485 Beclometasone dipropionate
- GC61536 Beclomethasone 17-propionate Beclomethasone 17-propionate (Beclomethasone-17-monopropionate), an active metabolite of Beclomethasone dipropionate, is a glucocorticoid receptor (GR) agonist.
- GC17465 Beclomethasone dipropionate Corticosteroid used for asthma and rhinitis
- GC10936 Betamethasone Glucocorticoid receptor agonist
- GC35502 Betamethasone acibutate Betamethasone acibutate, derives from Betamethasone, is an acetate ester.
- GC12122 Betamethasone Dipropionate Glucocorticoid receptor agonist
- GC35503 Betamethasone hydrochloride Betamethasone hydrochloride is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive activities.
- GC13638 Betamethasone Valerate anti-inflammatory corticosteroid
- GC65345 BI 653048 BI 653048 is a selective and orally active nonsteroidal?glucocorticoid (GC)?agonist with an IC50 value of 55 nM.
- GC11897 Budesonide Anti-inflammatory corticosteroid
- GC17571 Ciclesonide glucocorticoid
- GC11976 Clobetasol propionate Glucocorticoid receptor agonist
- GC39362 Clobetasone butyrate Clobetasone butyrate is a synthetic glucocorticoid and has topical anti-inflammatory activity especially in skin.
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GC12327
Corticosterone
Corticosterone (17 deoxycortisol) is a glucocorticoid with oral activity and produced by adrenal cortex, which plays an important role in regulating the neuronal function of limbic system (including hippocampus, prefrontal cortex and amygdala).
- GC33839 Cortisone (17-Hydroxy-11-dehydrocorticosterone)
- GC16772 Cortisone acetate Glucocorticoid receptor agonist
- GC39363 Cortodoxone Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).
- GC31844 Dagrocorat (PF-00251802) Dagrocorat (PF-00251802) (PF-00251802) is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor.
- GC63872 Dagrocorat hydrochloride Dagrocorat (PF-00251802) hydrochloride is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor.
- GC64330 Dazucorilant Dazucorilant (CORT113176) is a selective and high affinity non-steroidal glucocorticoid receptor (GR) modulator with a Ki value <1 nM in vitro.
- GC12931 Deflazacort anti-inflammatory and immunosuppressant
- GC63739 Deflazacort-D5
- GC63738 Deflazacort-D7
- GC35843 Desisobutyryl-ciclesonide Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide.
- GC15690 Desonide nonfluorinated corticosteroid anti-inflammatory agent
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GC40775
Dexamethasone
Dexamethasone, as one member of the glucocorticoid family, can protect against arthritis-related changes in cartilage structure and function, including matrix loss, inflammation and cartilage viability.
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GC11237
Dexamethasone acetate
IL Receptor modulator
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GC38573
Dexamethasone palmitate
Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM.
- GC31658 Dexamethasone phosphate disodium (Dexamethasone 21-phosphate disodium salt) Dexamethasone phosphate disodium (Dexamethasone 21-phosphate disodium salt) is a glucocorticoid receptor agonist.
- GC64466 Dexamethasone-d5
- GC31747 Flunisolide A fluorinated corticosteroid receptor agonist
- GC11257 Fluocinolone Acetonide Glucocorticoid receptor agonist
- GC10714 Fluocinonide Glucocorticoid receptor agonist
- GC40771 Fluorometholone Fluorometholone is a synthetic glucocorticoid that binds to glucocorticoid receptors (IC50 = 1.5 nM; Kd = 2.8 nM in a radioligand binding assay).
- GC39222 Fluticasone furoate A synthetic glucocorticoid
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GC13371
Fluticasone propionate
High affinity, selective glucocorticoid receptor agonist
- GC31885 Fosdagrocorat (PF-04171327) Fosdagrocorat (PF-04171327) (PF-04171327) is a dissociated glucocorticoid receptor agonist.
- GC11399 Glucocorticoid receptor agonist
- GC62663 Glucocorticoid receptor agonist-1 Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM extracted from patent WO2017210471A1, compound 41.
- GC13900 GSK 9027 glucocorticoid receptor agonist
- GC31936 GW-870086 GW-870086 is a potent anti-inflammatory agent, acting as a glucocorticoid receptor agonist, with a pIC50 of 10.1 in A549 cells expressing NF-κB.
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GC11551
Hydrocortisone
Hydrocortisone, a natural glucocorticoid secreted by adrenal and extra-adrenal tissues
- GC45994 Hydrocortisone Acetate A synthetic corticosteroid
- GC36268 Hydrocortisone cypionate Hydrocortisone cypionate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester.
- GC60914 Hydrocortisone hemisuccinate Hydrocortisone hemisuccinate (Hydrocortisone 21-hemisuccinate), a physiological glucocorticoid, is an orally active steroidal anti-in?ammatory drug (SAID).
- GC36269 Hydrocortisone phosphate Hydrocortisone phosphate (Hydrocortisone 21-phosphate), a physiological glucocorticoid, and is an orally active steroidal anti-in?ammatory drug (SAID).
- GC14975 Loteprednol etabonate potent glucocorticoid receptor agonist
- GC68316 Loteprednol Etabonate-d5
- GC19239 Mapracorat Mapracorat is a novel non-steroidal selective glucocorticoid receptor agonist.
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GC12974
Medroxyprogesterone acetate
Steroidal progestin
- GC61850 Medroxyprogesterone acetate D3
- GC15668 Meprednisone Glucocorticoid receptor (GR) agonist
- GC15505 Methylprednisolone A synthetic glucocorticoid
- GC11637 Mifepristone Progesterone receptor antagonist
- GC15746 Mometasone furoate glucocorticoid receptor agonist
- GC36809 OP-3633 OP-3633 is a potent and selective steroidal glucocorticoid receptor (GR) antagonist with an IC50 of 29 nM, with inhibition of GR transcriptional activity.
- GC65370 ORIC-101 ORIC-101 is a highly potent and selective glucocorticoid receptor antagonist, with an EC50 of 5.6 nM.
- GC15331 Prednisolone synthetic glucocorticoid
- GC44678 Prednisolone Phosphate (sodium salt) Prednisolone Phosphate (sodium salt) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
- GC36961 Prednisolone Tebutate Prednisolone tebutate is a synthetic glucocorticoid used as an antiinflammatory and immunosuppressant.
- GC16450 Prednisone Glucocorticoid receptor agonist
- GC36962 Prednisone acetate Prednisone acetate (Prednisone 21-acetate), the acetate salt form of prednisolone, is a glucocorticoid receptor agonist with anti-inflammatory and immunomodulating properties.
- GC10434 Triamcinolone synthetic glucocorticoid agonist
- GC12611 Triamcinolone Acetonide Antiinflammatory steroid
- GC33868 Triamcinolone Benetonide Triamcinolone benetonide is a synthetic glucocorticoid corticosteroid with anti-inflammatory activity.
- GC39564 Vamorolone Vamorolone (VBP15) is a first-in-class, orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer.