Adaptive Immunity

An immunosuppressant

A lipopeptide with enzyme inhibitory and immunosuppressant activities

An ionizable cationic lipid

An inhibitor of DGK-α, DGK-ζ, and DGK-ι

An inhibitor of Spns2

A glucosamine-based lipid conjugate

A P2RY8 ligand

S1PL-IN-31 is an inhibitor of sphingosine-1-phosphate (S1P) lyase (IC50 = 210 nM).

TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM).

PD-1/PD-L1 inhibitor N11 is an inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1; IC50 = 6.3 nM).

DB2313 is an inhibitor of the transcription factor PU.

PDIC-NS is an activator of stimulator of interferon genes (STING).

Ppc-1 is a prenylated quinolinecarboxylic acid originally isolated from P. pseudo-candidum that has diverse biological activities.

Alloisolithocholic acid-d4 is intended for use as an internal standard for the quantification of alloisolithocholic acid by GC- or LC-MS.

PQA-18 is an inhibitor of p21-activated kinase 2 (PAK2; IC50 = 10 nM), an immunosuppressant, and a derivative of Ppc-1.

SGC0946 is an inhibitor of the non-SET domain-containing methyltransferase DOT1L (IC50 = 0.3 nM).

Lipid N2-3L is an ionizable cationic lipid (pKa = 8.99) that has been used in the generation of supramolecular lipid nanoparticles (SMLNPs) encapsulating mRNA for use in vitro and in vivo.

Chlorotoxin is a peptide originally isolated from the venom of the scorpion L. quinquestriatus.