GLPBio

NF-κB

NF-κB is a family of conserved and ubiquitous transcription factors that involved in various biological processes including immunity, inflammation, cell growth, differentiation and apoptosis. It is associated with cancer, chronic inflammation and arthritis etc.

Products Related to NF-κB(336)

  • GC79813 structure
    GC79813Arvelexin
    CAS: 4837-74-5
    Purity: >98.00%

    Arvelexin is a biologically active compound.

  • GC79815 structure
    GC79815(E/Z)-Sinigrin free base
    CAS: 534-69-0
    Purity: >98.00%

    (E/Z)-Sinigrin ((E/Z)-Allyl-glucosinolate; (E/Z)-2-Propenyl-glucosinolate) free base is an orally active aliphatic thioglucoside anti-leukemia compound.

  • GC79816 structure
    GC79816Cryptolepine
    CAS: 480-26-2
    Purity: >98.00%

    Cryptolepine is an orally active multi-potent alkaloid with anti-cancer, anti-bacterial, anti-viral, anti-malarial, anti-inflammatory, anti-hyperglycemic, relieve pain and other properties.

  • GC79976 structure
    GC79976Chitosan oligosaccharide (MW 2000)
    Purity: >98.00%

    Chitosan oligosaccharide (MW 2000) is a natural oligomer derived from chitosan, with a molecular weight of 2000 Da.

  • GC80509 structure
    GC80509Nervonic acid-d 18
    Purity: >98.00%

    Nervonic acid -d 18 (Selacholeic acid-d 18 ) is the deuterium labeled Nervonic acid.

  • GC80846 structure
    GC80846Myristic acid- 13 C 2
    CAS: 287111-20-0
    Purity: >98.00%

    Myristic acid - 13 C 2 is the 13 C-labeled Myristic acid.

  • GC80863 structure
    GC80863(R)-Balcinrenone
    CAS: 1850385-65-7
    Purity: >99.50%

    (R)-Balcinrenone ((R)-AZD9977) is an isomer of Balcinrenone.

  • GC80868 structure
    GC80868Antcin K
    CAS: 741268-13-3
    Purity: >98.00%

    Antcin K is a selective inhibitor targeting the PI3K/Akt, NF-κB, MEK1/2-ERK, p38 and AP-1 pathways.

  • GC80869 structure
    GC80869Calebin A
    CAS: 336784-82-8
    Purity: >98.00%

    Calebin A is a PI3K/Akt/mTOR, MAPK, and NF-κB inhibitor with oral effectiveness.

  • GC80873 structure
    GC80873Tovophyllin A
    CAS: 40738-44-1
    Purity: >98.00%

    Tovophyllin A is an orally active xanthonoid compound.

  • GC80880 structure
    GC80880dCASP1-55
    Purity: >98.00%

    dCASP1-55 is a cereblon-dependent caspase-1 ( CASP1 ) PROTAC degrader.

  • GC80922 structure
    GC80922PROTAC HDAC6 degrader 7
    Purity: >98.00%

    PROTAC HDAC6 degrader 7 is an orally active, highly efficient, and selective PROTAC degrader targeting histone deacetylase 6 ( HDAC6 ) ( IC 50 = 118 nM).

  • GC81025 structure
    GC81025PSP-0119
    CAS: 3104855-98-0
    Purity: >98.50%

    PSP-0119 is a highly efficient and effective PROTAC degrader targeting IRAK4 ( IC 50 = 2.83 nM).

  • GC81298 structure
    GC81298BSJ-05-037
    CAS: 2756388-01-7
    Purity: >99.50%

    BSJ-05-037 is an ITK PROTAC degrader that effectively targets and degrades ITK in T-cell lymphoma cell lines.

  • GC81542 structure
    GC815427-O-Galloyl-D-sedoheptulose
    CAS: 233690-85-2
    Purity: >98.00%

    7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound.

  • GC81548 structure
    GC81548CIGB-552 TFA
    Purity: >98.00%

    CIGB-552 TFA is a cell-penetrating peptide with anti-tumor properties with the IC 50 of 23 μM in H460 cells.

  • GC81572 structure
    GC81572Glutathione trisulfide TFA
    Purity: >99.00%

    Glutathione trisulfide TFA (GSSSG TFA) is an orally active, blood-brain barrier permeable neuroprotective agent.

  • GC81752 structure
    GC817528-Deoxylactucin
    CAS: 65725-10-2
    Purity: >95.00%

    8-Deoxylactucin is an orally active sesquiterpene lactone.

  • GC81761 structure
    GC817614-Methoxycinnamic acid ethyl ester
    CAS: 1929-30-2
    Purity: >98.50%

    4-Methoxycinnamic acid ethyl ester (Ethyl p-methoxycinnamate) is an orally active natural compound found.

  • GC81771 structure
    GC81771RANKL-IN-1 formate
    Purity: >99.50%

    RANKL-IN-1 formate is a selective receptor activator of nuclear factor-κB ligand inhibitor ligand ( RANKL ) inhibitor with a K D value of 7.6 μM.

  • GC81850 structure
    GC81850p53 Bipartite NLS TFA
    Purity: >98.00%

    p53 Bipartite NLS TFA is a bipartite nuclear localization signal derived from p53.

  • GC91093 structure
    GC91093MR2938
    CAS: 1044870-65-6
    Purity: >95.00%

    An AChE inhibitor

  • GC91175 structure
    GC91175NCI 126224
    CAS: 65974-52-9
    Purity: >98.00%

    A TLR4 antagonist

  • GC91768 structure
    GC91768GSK205 (hydrobromide)
    Purity: >95.00%

    GSK205 is an inhibitor of transient receptor potential vanilloid 4 (TRPV4) and transient receptor potential ankyrin 1 (TRPA1; IC50s = 4.19 and 5.56 µM, respectively, for the rat channels).