NF-κB

N,N′-Diferuloylputrescine is a polyamine that has been found in Z. mays and has diverse biological activities.

3,3-Dimethyl-1-butanol is an oral inhibitor that inhibits the production of trimethylamine (TMA) by microorganisms and suppresses different microbial TMA lyases.

γ-Tocotrienol (γ-T3) is a subtype of tocotrienol and a major type of vitamin E with two substituted methyl groups.

Hecubine is a natural aspidosperma-type alkaloid found in E. officinalis , with anti-neuroinflammation properties.

Baicalin is a flavonoid glycoside and an allosteric carnitine palmitoyltransferase 1 (CPT1) activator.

Dihydroartemisinin (DHA) is an active metabolite of artemisinin and its derivatives (ARTs) and is an effective drug widely used in the clinic to treat malaria.

Neferine (NEF) is a natural bisbenzylisoquinoline alkaloid separated from the traditional Chinese medicine Nelumbinis plumula. Neferine has a variety of pharmacological properties.

Ginsenoside Rb1 is a natural active ingredient extracted from ginseng that can modulate the activity of multiple signaling pathways.

Saikosaponin D is a triterpenoid saponin derivative with antioxidant, antipyretic, and anti-inflammatory properties.

Sinomenine Hydrochloride is an inhibitor of NF-κB activation.

Shikonin is a quinone-containing natural product. Shikonin is a potent TMEM16A chloride channel inhibitor with an IC 50 of 6.5μM.

Ginsenoside Re is a natural compound found in Panax ginseng , possessing potent antioxidant and anti-inflammatory bioactivities.

Parthenolide is an NF-κB inhibitor with IC 50 values for Eca109, KYSE-510, SiHa and MCF-7 cells of approximately 10.3, 13.3, 8.42 and 9.54µM at 48h respectively.