GLPBio

JAK/STAT Signaling

Research Areas

Products Related to JAK/STAT Signaling(493)

  • GN10314 structure
    GN10314Picroside I
    CAS: 27409-30-9
    Purity: >99.00%
  • GN10436 structure
    GN10436Morusin
    CAS: 62596-29-6
    Purity: >98.50%

    Morusin is a significant prenylated flavone found in Morus alba ( Moraceae ) root cortex, which exhibits significant anti-tumor activity in the treatment of prostate cancer.

  • GN10442 structure
    GN10442Curculigoside
    CAS: 85643-19-2
    Purity: >99.50%
  • GN10501 structure
    GN10501Cryptotanshinone
    CAS: 35825-57-1
    Purity: >99.50%

    Cryptotanshinone is a natural compound extracted from the roots of Salvia miltiorrhiza Bunge, exhibiting antitumor activity by inhibiting Signal Transducer and Activator of Transcription 3 (STAT3) with an IC 50 value of 4.6μM.

  • GN10624 structure
    GN10624Scutellarin
    CAS: 27740-01-8
    Purity: >98.00%

    Scutellarin is a flavonoid with multiple biological activities.

  • GN10627 structure
    GN10627Atractylenolide I
    CAS: 73069-13-3
    Purity: >98.00%
  • GN10696 structure
    GN10696Garcinone C
    CAS: 76996-27-5
    Purity: >98%
  • GN10705 structure
    GN10705Alantolactone
    CAS: 546-43-0
    Purity: >98.00%
  • GN10741 structure
    GN10741Garcinone D
    CAS: 107390-08-9
    Purity: >98.00%
  • GN10742 structure
    GN10742Homoharringtonine
    CAS: 26833-87-4
    Purity: >99.50%

    Homoharringtonine is a protein synthesis inhibitor and a cytotoxic alkaloid, originally isolated from the evergreen tree Cephalotaxus hainanensis . It is often used in the research of lung cancer and breast cancer.

  • GC17222 structure
    GC17222GLPG0634 analogue
    CAS: 1206101-20-3
    Purity: >98.50%

    GLPG0634 analogue (Compoun 176) is a broad spectrum JAK inhibitor with IC50 values of <100 nM against JAK1, JAK2 and JAK3.

  • GC13586 structure
    GC13586Niclosamide
    CAS: 50-65-7
    Purity: >98.50%

    Niclosamide, an anthelmintic drug, is the small-molecule inhibitor of STAT3 with an IC 50 value of 0.25±0.07μM.

  • GC11990 structure
    GC11990TCS-PIM-1-4a
    CAS: 327033-36-3
    Purity: >99.50%

    Pim inhibitor