ERK
ERK (extracellular-signal-regulated kinase), also known as MAPK, is involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
Products Related to ERK(149)
- GN10494Astragaloside IVCAS: 84687-43-4Purity: >98.00%
Astragaloside IV, an active component isolated from Astragalus membranaceus, can protect the myocardium against ischemia/reperfusion injury and Inhibits HAdV-3 replication and reduces HAdV-3-induced apoptosis.
- GN10664HonokiolCAS: 35354-74-6Purity: >98.50%
Honokiol is a natural bisphenol chemical with multiple biological activities. It targets multiple signaling molecules and has effective antioxidant, anti-inflammatory, anti-angiogenic and anti-cancer activities. It also has broad-spectrum antibacterial and anti-human immunodeficiency virus (HIV) activities.
- GC17031VRT752271CAS: 869886-67-9Purity: >99.50%
VRT752271 (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. VRT752271 (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GN10494 | Astragaloside IV | 84687-43-4 | >98.00% | |
Astragaloside IV, an active component isolated from Astragalus membranaceus, can protect the myocardium against ischemia/reperfusion injury and Inhibits HAdV-3 replication and reduces HAdV-3-induced apoptosis. | ||||
| GN10664 | Honokiol | 35354-74-6 | >98.50% | |
Honokiol is a natural bisphenol chemical with multiple biological activities. It targets multiple signaling molecules and has effective antioxidant, anti-inflammatory, anti-angiogenic and anti-cancer activities. It also has broad-spectrum antibacterial and anti-human immunodeficiency virus (HIV) activities. | ||||
| GN10752 | Pachymic acid | 29070-92-6 | >98.00% | |
| GC17031 | VRT752271 | 869886-67-9 | >99.50% | |
VRT752271 (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. VRT752271 (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line. | ||||
| GC10647 | FR 180204 | 865362-74-9 | >98.00% | |
FR 180204 is a selective ERK inhibitor with IC 50 values of 0.51μM and 0.33μM for ERK1 and ERK2, respectively. | ||||