JNK
JNK (c-Jun N-terminal kinase) is a group of kinases belong to the mitogen-activated protein kinase family and also play a role in T cell differentiation and the cellular apoptosis pathway.
Products Related to JNK(71)
- GC69322JTP10-Δ -TATi TFAPurity: >99.50%
JTP10-△-TATi TFA is a selective peptide inhibitor of JNK2, with an IC50 value of 92 nM. Its selectivity for JNK2 is more than 10 times that of JNK1 and JNK3.
- GC79475MKK7-JNK activator 1CAS: 3100092-62-1Purity: >99.50%
MKK7-JNK activator 1 (Compound 10) is a MKK7-JNK pathway activator.
- GC81020JNK1 ligand-1-NH-Ph-COOHCAS: 3047792-63-9Purity: >98.00%
JNK1 ligand-1 (Compound P1) is a selective JNK1 inhibitor.
- GC815427-O-Galloyl-D-sedoheptuloseCAS: 233690-85-2Purity: >98%
7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound.
- GC81771RANKL-IN-1 formatePurity: >99.50%
RANKL-IN-1 formate is a selective receptor activator of nuclear factor-κB ligand inhibitor ligand ( RANKL ) inhibitor with a K D value of 7.6 μM.
- GC81827Buforin IIb TFAPurity: >98.00%
Buforin IIb TFA (BF2-B TFA) is an anticancer peptide, as well as an Antibacterial and Antifungal agent.
- GN10307Ginsenoside ReCAS: 52286-59-6Purity: >99.00%
Ginsenoside Re is a natural compound found in Panax ginseng , possessing potent antioxidant and anti-inflammatory bioactivities.
- GN10494Astragaloside IVCAS: 84687-43-4Purity: >98.00%
Astragaloside IV, an active component isolated from Astragalus membranaceus, can protect the myocardium against ischemia/reperfusion injury and Inhibits HAdV-3 replication and reduces HAdV-3-induced apoptosis.
- GN10804IsovitexinCAS: 38953-85-4 ; 29702-25-8Purity: >98.00%
Isovitexin extracted from rice hulls of Oryza sativa , possesses various biological activities, including anti-inflammatory and antioxidant activities.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC69322 | JTP10-Δ -TATi TFA | - | >99.50% | |
JTP10-△-TATi TFA is a selective peptide inhibitor of JNK2, with an IC50 value of 92 nM. Its selectivity for JNK2 is more than 10 times that of JNK1 and JNK3. | ||||
| GC71114 | JNK-IN-11 | 676594-38-0 | >98.00% | |
JNK-IN-11 (compound 1) is a potent JNK inhibitor with an IC50 value of 2.2, 21.4, 1.8 µM for JNK1, JNK2, JNK3, respectively. | ||||
| GC71195 | DN-1289 | 3026597-15-6 | - | |
DN-1289 is an orally active and selective inhibitor of dual leucine zipper kinase (DLK; IC50=17 nM) and leucine zipper-bearing kinase (LZK; IC50=40 nM). | ||||
| GC74163 | JNK-IN-13 | 345986-38-1 | >95.00% | |
JNK-IN-13 (compound 1) is a potent and selective JNK inhibitor with IC50s of 290 nM and 500 nM for JNK3 and JNK2, respectively. | ||||
| GC74330 | CMX-8933 | 146877-90-9 | >99.00% | |
CMX-8933 is an octapeptide fragment of the goldfish brain neurotrophic factor ependymin. | ||||
| GC79389 | ETI41 | 2773474-99-8 | >98% | |
ETI41 is an orally active, selective TLR inhibitor that targets the nucleoside-binding Site I on TLR7 ( IC 50 = 0.63 μM) and TLR9 ( IC 50 = 0.16 μM), sparing surface TLRs (including TLR1/TLR2, TLR2/TLR6, TLR4 and TLR5). | ||||
| GC79390 | ETI60 | 2773475-11-7 | >99.50% | |
ETI60 is an orally active, selective TLR inhibitor that targets the nucleoside-binding Site I on TLR7 ( IC 50 = 0.68 μM) and TLR9 ( IC 50 = 0.12 μM), sparing surface TLRs (including TLR1/TLR2, TLR2/TLR6, TLR4 and TLR5). | ||||
| GC79391 | MyD88-IN-3 | - | >99.00% | |
MyD88-IN-3 is an orally active, selective MyD88 Inhibitor. | ||||
| GC79475 | MKK7-JNK activator 1 | 3100092-62-1 | >99.50% | |
MKK7-JNK activator 1 (Compound 10) is a MKK7-JNK pathway activator. | ||||
| GC81020 | JNK1 ligand-1-NH-Ph-COOH | 3047792-63-9 | >98.00% | |
JNK1 ligand-1 (Compound P1) is a selective JNK1 inhibitor. | ||||
| GC81542 | 7-O-Galloyl-D-sedoheptulose | 233690-85-2 | >98% | |
7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound. | ||||
| GC81771 | RANKL-IN-1 formate | - | >99.50% | |
RANKL-IN-1 formate is a selective receptor activator of nuclear factor-κB ligand inhibitor ligand ( RANKL ) inhibitor with a K D value of 7.6 μM. | ||||
| GC81827 | Buforin IIb TFA | - | >98.00% | |
Buforin IIb TFA (BF2-B TFA) is an anticancer peptide, as well as an Antibacterial and Antifungal agent. | ||||
| GN10267 | Loureirin B | 119425-90-0 | >99.00% | |
| GN10307 | Ginsenoside Re | 52286-59-6 | >99.00% | |
Ginsenoside Re is a natural compound found in Panax ginseng , possessing potent antioxidant and anti-inflammatory bioactivities. | ||||
| GN10494 | Astragaloside IV | 84687-43-4 | >98.00% | |
Astragaloside IV, an active component isolated from Astragalus membranaceus, can protect the myocardium against ischemia/reperfusion injury and Inhibits HAdV-3 replication and reduces HAdV-3-induced apoptosis. | ||||
| GN10709 | Polyphyllin A | 50773-41-6 | >98.00% | |
| GN10804 | Isovitexin | 38953-85-4 ; 29702-25-8 | >98.00% | |
Isovitexin extracted from rice hulls of Oryza sativa , possesses various biological activities, including anti-inflammatory and antioxidant activities. | ||||
| GC11488 | TCS JNK 5a | 312917-14-9 | >98.00% | |
JNK2 and JNK3 inhibitor | ||||
| GC13529 | CC-401 | 395104-30-0 | >98% | |
JNK inhibitor,ATP-competitive | ||||
| GC10204 | AEG 3482 | 63735-71-7 | >99.00% | |
inhibitor of Jun kinase (JNK)-dependent apoptosis | ||||
| GC12674 | IQ 3 | 312538-03-7 | >98.50% | |
Selective JNK3 inhibitor | ||||
| GC12904 | BI 78D3 | 883065-90-5 | >99.00% | |
Competitive JNK inhibitor | ||||