Fluorescent Probes

MitoPerOx is a ratiometric fluorescent probe that can be used to assess changes in lipid peroxidation within mitochondria.

Naphthol AS-BI-phosphate is a fluorogenic substrate for acid and alkaline phosphatases.

FTY720 is an immune modulator that down-regulates sphingosine-1-phosphate (S1P) receptors, enhances the activity of the sphingosine transporter Abcb1 and the leukotriene C4 transporter Abcc1, and inhibits cytosolic phospholipase A2 activity.

A fluorescent compound

NIAD-4 is a fluorescent probe that crosses the blood-brain barrier to bind with high affinity to amyloid-β (Aβ) plaques (Ki = 10 nM).

PBD-BODIPY is a probe for the spectrophotometric measurement of autoxidation reactions.

Reactive oxygen species (ROS) play important roles in the initiation and progression of many disease processes.

Phalloidin-AMCA conjugate is a blue fluorophore that specifically labels filamentous actin (F-actin).

Phalloidin-fluorescein conjugate is a green fluorophore that specifically labels filamentous actin (F-actin).

Phalloidin-retramethylrhodamine conjugate is an orange fluorescent probe (ex/em = 546/575 nm) that selectively binds to F-actin.

Quin-2 is a high-affinity fluorescent calcium indicator (Kd = 115 nM for calcium).

ReAsH-EDT2 is a fluorescent, membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences, which are engineered into target proteins.

The renin fluorogenic substrate consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other.

Resorufin benzyl ether is a fluorometric probe that acts as a substrate for cytochrome P450 (CYP)3A4.

Rhod-2 (potassium salt) is a water-soluble, red fluorescent calcium indicator.

Rhod-2 (sodium salt) is a water-soluble, red fluorescent calcium indicator.

Rhod-5N is a low affinity fluorescent calcium probe (Kd = 320 μM).

Rhod-5N AM is a cell-permeant acetoxymethyl ester of the fluorescent calcium indicator rhod-5N.

Rhodamine 101 (inner salt) is a bright fluorescent dye with excitation and emission maxima of 565 and 595 nm, respectively.

Rhodamine B hydrazide is a water-soluble fluorescent probe with excitation/emission spectra of 510/578 nm, respectively.

Rhodamine B isothiocyanate (RITC) is a cell-permeant fluorogenic dye most often used as a conjugate to antibodies and proteins for fluorescence detection in microscopy.

Rhod-FF is a difluorinated analog of the cell-impermeant calcium indicator rhod-2.

Rhod-FF AM is a cell-permeant acetoxymethyl ester of the fluorescent calcium indicator rhod-FF.

SBFI AM is a membrane-permeant, fluorescent Na+ indicator dye.