MDR multidrug resistance

MDR (multidrug resistance) is a property that first identified in tumor cell, hat the resistance of tumor cell is to a variety of chemotherapy agent due to active efflux via transporter proteins.

Products Related to MDR multidrug resistance(44)

GC46809 Afatinib-d6
CAS: 1313874-96-2
Purity: >99.00%
An internal standard for the quantification of afatinib
GC48119 Suprafenacine
CAS: 1477482-50-0
Purity: >98.00%
An inhibitor of tubulin polymerization with anticancer activity
GC48219 Ulipristal Acetate-d6
CAS: 1621894-64-1
Purity: >99.00%
An internal standard for the quantification of ulipristal acetate
GC48479 Migrastatin
CAS: 314245-65-3
Purity: >90.00%
A fungal metabolite with antimuscarinic and anticancer activities
GC49106 Gentisein
CAS: 529-49-7
Purity: >95.00%
A xanthone with diverse biological activities
GC49251 Oxaliplatin-d10
CAS: 1132819-16-9
Purity: >99.00%
An internal standard for the quantification of oxaliplatin
GC49275 8-Oxycoptisine
CAS: 19716-61-1
Purity: >98.00%
8-Oxycoptisine is a natural protoberberine alkaloid with anti-cancer activity.
GC49308 Ungeremine
CAS: 2121-12-2
Purity: >98.00%
A betaine-type alkaloid with diverse biological activities
GC49670 Indium (III) thiosemicarbazone 5b
CAS: 2345755-20-4
Purity: >95.00%
An anticancer agent
GC52104 Ponatinib (hydrochloride)
CAS: 1114544-31-8
Purity: >98.00%
Ponatinib (hydrochloride) is a multi-target tyrosine kinase inhibitor that inhibits the activity of Abl (IC₅₀=0.37nM), PDGFRα (IC₅₀=1.1nM), VEGFR2 (IC₅₀=1.5nM), FGFR1 (IC₅₀=2.2nM), and Src (IC₅₀=5.4nM).
GC52455 Pixantrone-d8 (maleate)
Purity: >99.00%
An internal standard for the quantification of pixantrone
GC90543 EGFR Peptide (human, mouse) (myristoylated) (trifluoroacetate salt)
Purity: >95.00%
A PKC inhibitor
GC90660 Fz25
CAS: 2762498-70-2
Purity: >98.00%
A triazole-modified sterol and an anticancer agent
GC91057 HP661
Purity: >98.00%
A mitochondrial complex I inhibitor
GC91096 S-72
CAS: 2446799-14-8
Purity: >98.00%
An inhibitor of microtubule polymerization
GC91135 4-(3,4-Difluorobenzo)curcumin
CAS: 1170354-22-9
Purity: >95.00%
A semisynthetic coumarin with antiparasitic and anticancer activities
GC91152 Flavokawain 1i
CAS: 1098176-51-2
Purity: >98.00%
A flavokawain derivative with anticancer and antiviral activities
GC91154 33-BCRP Inhibitor
Purity: >98.00%
A BCRP inhibitor
GC91403 HR68
CAS: 2454582-64-8
Purity: >98.00%
HR68 is an anticancer agent and a derivative of the peroxisome proliferator-activated receptor (PPAR) agonist fenofibric acid .
GC91435 YCH1899
Purity: >98.00%
YCH1899 is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (IC50s = 1 It is selective for PARP1 and PARP2 over PARP3, -4, -5A, -5B, -6, -7, -10, and -12 (IC50s = 1-14.1 nM).

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC46809	Afatinib-d6	1313874-96-2	>99.00%
GC46809	An internal standard for the quantification of afatinib
GC48119	Suprafenacine	1477482-50-0	>98.00%
GC48119	An inhibitor of tubulin polymerization with anticancer activity
GC48219	Ulipristal Acetate-d6	1621894-64-1	>99.00%
GC48219	An internal standard for the quantification of ulipristal acetate
GC48479	Migrastatin	314245-65-3	>90.00%
GC48479	A fungal metabolite with antimuscarinic and anticancer activities
GC49106	Gentisein	529-49-7	>95.00%
GC49106	A xanthone with diverse biological activities
GC49251	Oxaliplatin-d10	1132819-16-9	>99.00%
GC49251	An internal standard for the quantification of oxaliplatin
GC49275	8-Oxycoptisine	19716-61-1	>98.00%
GC49275	8-Oxycoptisine is a natural protoberberine alkaloid with anti-cancer activity.
GC49308	Ungeremine	2121-12-2	>98.00%
GC49308	A betaine-type alkaloid with diverse biological activities
GC49670	Indium (III) thiosemicarbazone 5b	2345755-20-4	>95.00%
GC49670	An anticancer agent
GC52104	Ponatinib (hydrochloride)	1114544-31-8	>98.00%
GC52104	Ponatinib (hydrochloride) is a multi-target tyrosine kinase inhibitor that inhibits the activity of Abl (IC₅₀=0.37nM), PDGFRα (IC₅₀=1.1nM), VEGFR2 (IC₅₀=1.5nM), FGFR1 (IC₅₀=2.2nM), and Src (IC₅₀=5.4nM).
GC52455	Pixantrone-d8 (maleate)	-	>99.00%
GC52455	An internal standard for the quantification of pixantrone
GC90543	EGFR Peptide (human, mouse) (myristoylated) (trifluoroacetate salt)	-	>95.00%
GC90543	A PKC inhibitor
GC90660	Fz25	2762498-70-2	>98.00%
GC90660	A triazole-modified sterol and an anticancer agent
GC91057	HP661	-	>98.00%
GC91057	A mitochondrial complex I inhibitor
GC91096	S-72	2446799-14-8	>98.00%
GC91096	An inhibitor of microtubule polymerization
GC91135	4-(3,4-Difluorobenzo)curcumin	1170354-22-9	>95.00%
GC91135	A semisynthetic coumarin with antiparasitic and anticancer activities
GC91152	Flavokawain 1i	1098176-51-2	>98.00%
GC91152	A flavokawain derivative with anticancer and antiviral activities
GC91154	33-BCRP Inhibitor	-	>98.00%
GC91154	A BCRP inhibitor
GC91403	HR68	2454582-64-8	>98.00%
GC91403	HR68 is an anticancer agent and a derivative of the peroxisome proliferator-activated receptor (PPAR) agonist fenofibric acid .
GC91435	YCH1899	-	>98.00%
GC91435	YCH1899 is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (IC50s = 1 It is selective for PARP1 and PARP2 over PARP3, -4, -5A, -5B, -6, -7, -10, and -12 (IC50s = 1-14.1 nM).