Ox Stress Reagents

Pyridoxatin is a fungal metabolite originally isolated from Acremonium with diverse biological activities.

Resveratrol-3-O-sulfate (sodium) is the metabolite of Resveratrol.

S1QEL1.1 is a small molecule that suppresses superoxide production during reverse electron transport through the IQ site of the mitochondrial respiratory complex I (IC50 = 70 nM) without affecting oxidative phosphorylation.

Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals.

Superoxide radical anion is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms.

SRS16-86 is a third-generation ferrostatin-class ferroptosis inhibitor.

Sulpho NONOate produces nitrous oxide but no NO at physiological pH.

TAN 420E is a bacterial metabolite originally isolated from Streptomyces.

2,2,6,6-Tetramethylpiperidin-1-oxyl (TEMPO) is a stable radical that will react with reactive oxygen species (ROS).

Tetrachlorohydroquinone (TCHQ) is a metabolite of the organochlorine biocide pentachlorophenol.

Tosyl Phenylalanyl Chloromethyl Ketone (L-1-Tosylamido-2-phenylethyl chloromethyl ketone; L-Tosyl Phenylalanyl Chloromethyl Ketone) is a potent serine protease inhibitor that reacts with the retinoblastoma protein (RB)-binding core of HPV-18 E7 protein and abolish its RB-binding capability.

trans-Clovamide (trans-trans-Clovamide), a natural phenolic compound, is a potent antioxidant.

During oxidative stress, the abundant unsaturated fatty acid linoleic acid undergoes lipid peroxidation to produce α,β-unsaturated epoxy-keto-octadecenoic acids (EKODEs).

U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation.

Uric Acid (sodium salt) (Monosodium urate), scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress.

Urotensin II is a somatostatin-like neuropeptide agonist of the urotensin II receptor (UTR; Ki = 2 nM).

V-PYRRO/NO is a NO donor in vivo.

WSP-1 is a selective and rapid responsive fluorescent probe for active sulfides, specifically designed for the detection of hydrogen sulfide (H2S) within biological samples and intracellular environments.

β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane.

(-)-FINO2 is an organic peroxide that can selectively induce ferroptosis and is used to study the mechanisms of ferroptosis and anticancer therapy.

3-Hydroxyterphenyllin is a metabolite of Aspergillus candidus.3-Hydroxyterphenyllin suppresses proliferation and causes cytotoxicity against A2780/CP70 and OVCAR-3 cells. 3-Hydroxyterphenyllin induces S phase arrest and apoptosis. 3-Hydroxyterphenyllin has the potential for the research of ovarian cancer.