SOTS-1 (technical grade) |
| Catalog No.: GC44918 |
Superoxide radical anion is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms.
Sample solution is provided at 25 µL, 10mM.
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Quality Control & SDS
- View current batch:
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Purity: >80.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Superoxide radical anion is a toxic by-product of mitochondrial respiration that is formed from approximately 1-4% of the oxygen metabolized by aerobic organisms. SOTS-1 is an azo-compound that can be thermally decomposed in aqueous solution to generate superoxide radical anion at a constant, controlled rate. More specifically, SOTS-1 thermally decomposes to form an intermediate that reacts with oxygen at the diffusion-controlled limit to generate superoxide radical anion. The decay of SOTS-1 into the intermediate follows first order kinetics, and exhibits a half-life of 4900 seconds at physiological pH and temperature. This allows for study of the effect of superoxide on biologically relevant systems in a controlled environment that closely mimics conditions in vivo.
| Cas No. | 223507-96-8 | SDF | |
| Canonical SMILES | O=C(O)C1=CC=C(CON=NOCC2=CC=C(C(O)=O)C=C2)C=C1 | ||
| Formula | C16H14N2O6 | M.Wt | 330.3 |
| Solubility | DMF: 2 mg/ml,DMF:PBS(pH 7.2)(1:2): 0.3 mg/ml,DMSO: 10 mg/ml | Storage | Store at -80°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
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Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
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