Lipid Peroxidation

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ.

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes and activate polymorphonuclear leukocytes.

Cholesteryl linoleate hydroperoxides are derived from the autoxidation of cholesteryl linoleate and contain a mixture of racemic 9- and 13-HpODE cholesteryl esters.

The metallo-protein Cu/Zn-superoxide dismutase (SOD1) is a ubiquitous enzyme responsible for scavenging superoxide radicals.

DAz-2 is a cell-permeable chemical probe used to detect cysteine oxidation in proteins.

Phytic acid (Inositol hexaphosphate) hexasodium is a phosphorus storage compound of seeds and cereal grains.

DPPP (Diphenyl-1-pyrenylphosphine) is a non-fluorescent lipophilic fluorescent probe. DPPP can undergo a stoichiometric reaction with lipid hydroperoxides to produce highly fluorescent DPPP-O (excitation/emission wavelengths = 351/380nm).

Erastin2 is a potent system xc- inhibitor and ferroptosis-inducing agent.

Gallotannin (Tannic acid) is a natural polyphenolic compound that has been found in various plants and has antioxidant, anti-inflammatory, anti-angiogenic, antiviral and anti-tumor biological activities. Gallotannin inhibits the activity of DNA polymerase α, β and κ with IC 50 values of 13, 130 and 30nM, respectively .

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.

Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.

Lutein is a naturally occurring carotenoid with multiple biological activities and is widely found in green leafy vegetables, corn, and egg yolks.

MitoPBN is a mitochondria-targeted antioxidant.

MitoPerOx is a ratiometric fluorescent probe that can be used to assess changes in lipid peroxidation within mitochondria.

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.

p-Cymene is a monoterpene that is found in a variety of plants, including C.

Formed in vivo by the reaction of NO with superoxide

PGPC is an oxidized phospholipid that can be formed under conditions of oxidative stress.

Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic.

Pyridoxatin is a fungal metabolite originally isolated from Acremonium with diverse biological activities.

SRS16-86 is a third-generation ferrostatin-class ferroptosis inhibitor.

TAN 420E is a bacterial metabolite originally isolated from Streptomyces.

During oxidative stress, the abundant unsaturated fatty acid linoleic acid undergoes lipid peroxidation to produce α,β-unsaturated epoxy-keto-octadecenoic acids (EKODEs).

U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation.