MitoPBN |
| Catalog No.GC44202 |
MitoPBN is a mitochondria-targeted antioxidant.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 652968-37-1
Sample solution is provided at 25 µL, 10mM.
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MitoPBN is a mitochondria-targeted antioxidant. It accumulates in the mitochondria following the generation of a mitochondrial membrane potential by succinate, an effect that is blocked by addition of the mitochondrial membrane potential uncoupler FCCP . MitoPBN inhibits superoxide activation of mitochondrial uncoupling protein 1 (UCP1), UCP2, and UCP3 when used at a concentration of 250 nM in vitro but does not react with superoxide. It traps hydroxyl (IC50 = ~77 µM) and carbon-centered radicals and inhibits the initiation of lipid peroxidation in isolated bovine heart mitochondria.
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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