Acyltransferase

E-5324 is potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) with IC50s of 44 to 190 nM.

FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM.

MGAT2-IN-2 is a potent and selective acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) inhibitor with an IC50 of 3.4 nM.

2-Furoic acid (Furan-2-carboxylic acid) (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation.

K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with an IC50 of 0.45±0.06 μM.

RP-64477 is a potent inhibitor of the cholesterol esterifying enzyme Acyl-coenzyme A:cholesterol O-acyltransferase (ACAT).

Diacylglycerol acyltransferase inhibitor-1 is a diacylglycerol acyltransferase (DGAT1) inhibitor.

ABT-046 is a potent, selective, and orally active acyl CoA:diacylglycerol acyltransferase 1 (DGAT-1) inhibitor with IC50s of both 8 nM against human and mouse DGAT-1.

DGAT-1 inhibitor 2 is an effective inhibitor of DGAT-1;antiobesity agents.

DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1).

Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity.

10,12-Tricosadiynoic acid is a highly specific, selective, and orally active inhibitor of acyl-CoA oxidase-1 (ACOX1).

IMP-1088 is a picomolar dual inhibitor of the human N- myristoyltransferases NMT1 with IC 50 value of 0.24nM and NMT2 ith IC 50 value < 1nM.

TSI-01 is a selective inhibitor of lysophosphatidylcholine acyltransferase 2 (LPCAT2) with IC 50 values of 0.47 and 3.02 μM for human LPCAT2 and LPCAT1, respectively.

Andrastin A is a meroterpenoid farnesyltransferase inhibitor.

CAY10685 is a cell-active analog of the lysine acetyltransferase inhibitor CPTH2 that contains an alkyne moiety for use in click chemistry reactions.

DL-Glyceraldehyde 3-phosphate is a time-dependent inhibitor of the cationic and anionic isozymes of aspartate aminotransferase.

Enniatins are cyclohexadepsipeptides commonly isolated from fungi that are known to have antibiotic properties and to induce apoptosis in several cancer lines.

Enniatins are cyclohexadepsipeptides commonly isolated from fungi and are known to have antibiotic properties.

Fumonisin B2 is a selective ceramide synthase inhibitor and carcinogenic mycotoxin.

A fungal metabolite

A neuropeptide with diverse biological activities

A neuropeptide with diverse biological activities

An acyl-CoA thioester