FR-190809 |
| Catalog No.GC31551 |
FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 215589-63-2
Sample solution is provided at 25 µL, 10mM.
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FR-190809 is a potent, nonadrenotoxic, orally efficacious acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitor, with an IC50 of 45 nM[1].
FR-190809 inhibits foam cell formation with an IC50 of 215 nM[1].
[1]. Tanaka A, et al. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 3. Discovery of a novel series of N-alkyl-N-[(fluorophenoxy)benzyl]-N'-arylureas with weak toxicological effects on adrenal glands. J Med Chem. 1998 Oct 22;41(22):4408-20.
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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