Dipeptidyl Peptidase

Dipeptidyl Peptidase (DPP) is an antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation,signal transduction and apoptosis. DPP is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. The substrates of DPP are proline-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPP plays a major role in glucose metabolism. DPP is responsible for the degradation of incretins such as GLP-1. Furthermore, DPP appears to work as a suppressor in the development of cancer and tumours. DPP plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others.

Products Related to Dipeptidyl Peptidase(55)

GC69901 Sitagliptin fenilalanil hydrochloride
CAS: 1339954-75-4
Purity: >98.50%
Sitagliptin phenylalanine hydrochloride is a dipeptidyl peptidase-4 (DPP-4) inhibitor.
GC70545 Fotagliptin benzoate
CAS: 1403496-40-1
Purity: >99.00%
Fotagliptin benzoate is a Dipeptidyl Peptidase IV (DPP-4) inhibitor (IC50=2.27 nM).
GC74514 Begelomab
CAS: 1403744-56-8
Purity: >95.00%
Begelomab (SAND-26) is a murine IgG2b monoclonal antibody against DPP-4/CD26.
GC79593 DPP-4-IN-18
CAS: 486460-31-5
Purity: >98%
DPP-4-IN-18 (Sitagliptin impurity 3) (Compound 4) impurity 3 is a potent, selective and orally active DPP-4 inhibitor with an IC 50 of 27 nM.
GC79667 AGFAGDDAPR
CAS: 330204-04-1
Purity: >98.00%
AGFAGDDAPR is a bioactive peptide that is a competitive and orally effective inhibitor of dipeptidyl peptidase-IV ( DPP-IV ).
GC80487 D-γ-Glu-Tyr
CAS: 2417507-97-0
Purity: >99.50%
D-γ-Glu-Tyr is a D-isomer of γ-Glu-Tyr, the difference being the γ-Glu content.γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV ( DPP-IV ) ( IC 50 =6.77 mM), is a potentially functional component of the type 2 diabetes diet [1] .
GC81772 Epibestatin hydrochloride
CAS: 100992-60-7
Purity: >98.00%
Epibestatin hydrochloride is an epimer of Bestatin, a DPP4 inhibitor and protease inhibitor, with an IC 50 of 17 μM against DPP4.

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC69901	Sitagliptin fenilalanil hydrochloride	1339954-75-4	>98.50%
GC69901	Sitagliptin phenylalanine hydrochloride is a dipeptidyl peptidase-4 (DPP-4) inhibitor.
GC70545	Fotagliptin benzoate	1403496-40-1	>99.00%
GC70545	Fotagliptin benzoate is a Dipeptidyl Peptidase IV (DPP-4) inhibitor (IC50=2.27 nM).
GC74514	Begelomab	1403744-56-8	>95.00%
GC74514	Begelomab (SAND-26) is a murine IgG2b monoclonal antibody against DPP-4/CD26.
GC79593	DPP-4-IN-18	486460-31-5	>98%
GC79593	DPP-4-IN-18 (Sitagliptin impurity 3) (Compound 4) impurity 3 is a potent, selective and orally active DPP-4 inhibitor with an IC 50 of 27 nM.
GC79667	AGFAGDDAPR	330204-04-1	>98.00%
GC79667	AGFAGDDAPR is a bioactive peptide that is a competitive and orally effective inhibitor of dipeptidyl peptidase-IV ( DPP-IV ).
GC80487	D-γ-Glu-Tyr	2417507-97-0	>99.50%
GC80487	D-γ-Glu-Tyr is a D-isomer of γ-Glu-Tyr, the difference being the γ-Glu content.γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV ( DPP-IV ) ( IC 50 =6.77 mM), is a potentially functional component of the type 2 diabetes diet [1] .
GC81772	Epibestatin hydrochloride	100992-60-7	>98.00%
GC81772	Epibestatin hydrochloride is an epimer of Bestatin, a DPP4 inhibitor and protease inhibitor, with an IC 50 of 17 μM against DPP4.