GLPBio

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products Related to Drug Metabolite(546)

  • GC61536 structure
    GC61536Beclomethasone 17-propionate
    CAS: 5534-18-9
    Purity: >95.00%

    Beclomethasone 17-propionate (Beclomethasone-17-monopropionate), an active metabolite of Beclomethasone dipropionate, is a glucocorticoid receptor (GR) agonist.

  • GC61813 structure
    GC61813O-Desmethyl Mebeverine alcohol hydrochloride
    CAS: 856620-39-8
    Purity: >98.00%

    O-Desmethyl Mebeverine alcohol hydrochloride is a metabolite of Mebeverine, which is a potent α1 repector inhibitor, causing relaxation of the gastrointestinal tract.

  • GC61864 structure
    GC61864DL-Laudanosine
    CAS: 1699-51-0
    Purity: >99.00%

    DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood–brain barrier and may cause excitement and seizure activity.

  • GC62033 structure
    GC620333α-Hydroxy pravastatin sodium
    CAS: 81093-43-8
    Purity: >98%

    3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin.

  • GC62152 structure
    GC62152Homovanillyl alcohol
    CAS: 2380-78-1
    Purity: >99.50%

    Homovanillyl alcohol is a biological metabolite of Hydroxytyrosol.

  • GC62278 structure
    GC62278FTISADTSK acetate
    Purity: >99.50%

    FTISADTSK acetate is an endogenous stable signature peptide from Trastuzumab monitored by selected reaction monitoring (SRM).

  • GC62481 structure
    GC62481AST5902 trimesylate
    Purity: >99.50%

    AST5902 trimesylate is the principal metabolite of Alflutinib (AST2818) both in vitro and in vivo. AST5902 trimesylate exerts antineoplastic activity. Alflutinib is an EGFR inhibitor.

  • GC62737 structure
    GC62737(R)-(-)-O-Desmethyl Venlafaxine D6
    CAS: 1062609-96-4
    Purity: >98%
  • GC62777 structure
    GC627772-Methoxy-4-vinylphenol
    CAS: 7786-61-0
    Purity: >98.00%

    2-Methoxy-4-vinylphenol (2M4VP), a naturally Germination inhibitor, exerts potent anti-inflammatory effects.

  • GC62824 structure
    GC62824Acetaminophen glucuronide
    CAS: 16110-10-4
    Purity: >98%

    Acetaminophen glucuronide (APAP-glu) is an inactive glucuronide metabolite of Acetaminophen.

  • GC62845 structure
    GC62845Apoatropine hydrochloride
    CAS: 5978-81-4
    Purity: >99.50%
  • GC62923 structure
    GC62923Dasatinib metabolite M6
    CAS: 910297-53-9
    Purity: >99.00%

    Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib.

  • GC63028 structure
    GC63028IYPTNGYTR acetate
    Purity: >99.00%

    IYPTNGYTR acetate, a deamidation-sensitive signature peptide, is a deamidation product of Trastuzumab.

  • GC63311 structure
    GC63311Omeprazole metabolite Omeprazole sulfone (methoxy-d3)
    CAS: 1189891-71-1
    Purity: >98%

    Omeprazole metabolite Omeprazole sulfone (methoxy-d3) (Omeprazole sulfone (methoxy-d3)) is the deuterium labeled Omeprazole metabolite Omeprazole sulfone.

  • GC63337 structure
    GC63337N-Acetyl Norgestimate-d6
    CAS: 1263195-02-3
    Purity: >98%
  • GC63389 structure
    GC63389DP-1
    CAS: 1472616-61-7
    Purity: >99.50%

    DP-1, a degradation product of SDC-TRAP-0063, is a fragment of Ganetespib.

  • GC63624 structure
    GC63624tert-Buthyl Pitavastatin
    CAS: 586966-54-3
    Purity: >98%

    tert-Buthyl Pitavastatin is the ?metabolite?of Pitavastatin.

  • GC63684 structure
    GC63684Omeprazole sulfide-d3
    CAS: 922730-98-1
    Purity: >98%

    Omeprazole sulfide-d3 (Ufiprazole-d3) is the deuterium labeled Omeprazole sulfide.

  • GC63958 structure
    GC639586α-Hydroxy Paclitaxel-d5
    CAS: 1315376-90-9
    Purity: >98%

    6α-Hydroxy Paclitaxel-d5 is the deuterium labeled 6α-Hydroxy paclitaxel. 6α-Hydroxy paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy paclitaxel retains a time-dependent effect on organic anion-transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3. 6α-Hydroxy paclitaxel can be used for the research of cancer.

  • GC64076 structure
    GC64076Nortriptyline
    CAS: 72-69-5
    Purity: >98%

    Nortriptyline (Desmethylamitriptyline), the main active metabolite of Amitriptyline, is a tricyclic antidepressant used to relieve the symptoms of depression.

  • GC64335 structure
    GC64335N-Desmethyl imatinib-d8
    CAS: 1185103-28-9
    Purity: >99.00%

    N-Desmethyl imatinib D8 (Norimatinib D8) is a deuterium labeled Imatinib metabolite N-Desmethyl Imatinib.

  • GC64336 structure
    GC643362-Hydroxyemodin
    CAS: 641-90-7
    Purity: >98%

    2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes.

  • GC64469 structure
    GC64469Ribavirin carboxylic acid
    CAS: 39925-19-4
    Purity: >99.00%

    Ribavirin carboxylic acid (TR-COOH) is a metabolite of Ribavirin, Ribavirin has strong antiviral activity.

  • GC64511 structure
    GC64511Hydroxy ritonavir
    CAS: 176655-56-4
    Purity: >97.00%

    Hydroxy ritonavir is a metabolite of Ritonavir.