GLPBio

Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Products Related to Drug Metabolite(546)

  • GC64720 structure
    GC64720Imipramine N-oxide
    CAS: 6829-98-7
    Purity: >99.00%

    Imipramine N-oxide is the metabolite of Imipramine.

  • GC64759 structure
    GC64759Dimethadione
    CAS: 695-53-4
    Purity: >99.50%

    Dimethadione is the primary metabolite of trimethadione.

  • GC65324 structure
    GC65324RP101988
    CAS: 2990018-57-8
    Purity: >98.50%

    RP101988 is the major active metabolite of Ozanimod and is a highly selective, potent agonist of the S1PR1 (sphingosine-1-phosphate receptor 1), with EC 50 s of 0.19nM and 32.8nM for S1PR1 and S1PR5, respectivlely.

  • GC65956 structure
    GC65956Edoxaban M4
    CAS: 834919-19-6
    Purity: >99.00%

    Edoxaban M4, an active metabolite of Edoxaban, shows reproducible, but concentration-dependent matrix effects. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor .

  • GC66057 structure
    GC6605710,11-Dihydrocarbamazepine
    CAS: 3564-73-6
    Purity: >98%

    10,11-Dihydrocarbamazepine is the active metabolite of Oxcarbazepine. 10,11-Dihydrocarbamazepine also is an intermediate. Oxcarbazepine is rapidly and almost completely converted to 10,11-Dihydrocarbamazepine with probable Anticonvulsant efficacy.

  • GC66063 structure
    GC66063Tulipalin A
    CAS: 547-65-9
    Purity: >95.00%

    Tulipalin A (α-Methylene butyrolactone) is a glycoside. Tulipalin A is a causative allergen that induces Allergic contact dermatitides. Tulipalin A (α-Methylene butyrolactone) at low dose affects the functionality of immune cells, such as Jurkat T cells.

  • GC66449 structure
    GC66449Ferulic acid 4-O-sulfate
    CAS: 86321-29-1
    Purity: >95.00%

    Ferulic acid 4-O-sulfate (Ferulic acid 4-sulfate) is a metabolite of Ferulic acid (HY-N0060). Ferulic acid 4-O-sulfate relaxes arteries and lowers blood pressure in mice.

  • GC67761 structure
    GC67761(Z)-10-Hydroxynortriptyline-d3
    Purity: >98%
  • GC67766 structure
    GC67766Abiraterone sulfate
    CAS: 1993430-25-3
    Purity: >98.00%
  • GC67902 structure
    GC679023-Amino-2-oxazolidinone-d4
    CAS: 1188331-23-8
    Purity: >98%
  • GC67988 structure
    GC679886-Hydroxybenzbromarone
    CAS: 152831-00-0
    Purity: >99.50%
  • GC68082 structure
    GC680823,4,5-Trimethoxyphenylacetic acid
    CAS: 951-82-6
    Purity: >99.00%
  • GC68324 structure
    GC683243-Methoxytyramine-d4 hydrochloride
    CAS: 1216788-76-9
    Purity: >98%
  • GC68509 structure
    GC68509(25R)-12α-Hydroxyspirost-4-en-3-one
    CAS: 50888-50-1
    Purity: >98%

    (25R)-12α-Hydroxyspirost-4-en-3-one is a secondary metabolite produced by Nocardia globerula from Hecogenin.

  • GC69098 structure
    GC69098Febuxostat impurity 7
    CAS: 1350352-70-3
    Purity: >98%

    Febuxostat impurity 7 is an impurity of Febuxostat. Febuxostat is a selective inhibitor of xanthine oxidase (XO) with a Ki value of 0.6 nM.

  • GC69607 structure
    GC69607O-Demethyl Lenvatinib hydrochloride
    Purity: >95.00%

    O-Demethyl Lenvatinib hydrochloride is a metabolite of Lenvatinib. Lenvatinib (E7080) is an orally active, multi-targeted tyrosine kinase inhibitor that targets VEGFR1-3, FGFR1-4, PDGFR, KIT and RET. Lenvatinib has demonstrated effective anti-cancer activity.

  • GC69835 structure
    GC69835RPR132595A hydrochloride
    Purity: >99.00%

    RPR132595A (NPC) hydrochloride is an active metabolite of CPT-11, which is produced by cytochrome P-450 3A4 (CYP3A4) and ultimately excreted through urine.

  • GC70209 structure
    GC70209Didesethyl chloroquine-d4
    CAS: 1215797-41-3

    Didesethyl chloroquine-d4 is the deuterium labeled Didesethyl chloroquine.

  • GC70222 structure
    GC70222cPrPMEDAP
    CAS: 182798-83-0
    Purity: >99.00%

    cPrPMEDAP is an intermediate metabolite of GS-9219.

  • GC70400 structure
    GC70400Mebendazole-amine
    CAS: 52329-60-9

    Mebendazole-amine is a metabolite of Mebendazole.

  • GC70597 structure
    GC705975-Hydroxy Omeprazole-d3
    CAS: 2748479-83-4
    Purity: >96.00%

    5-Hydroxy Omeprazole-d3 is deuterium labeled 5-Hydroxyomeprazole.

  • GC70645 structure
    GC70645Gefitinib impurity 1
    CAS: 675126-26-8
    Purity: >99.00%

    Gefitinib impurity 1 is the impurity of Gefitinib.

  • GC70646 structure
    GC70646N-Methyl Palbociclib
    CAS: 571189-51-0
    Purity: >99.00%

    N-Methyl Palbociclib is an impurity of Palbociclib .

  • GC70728 structure
    GC70728ent-Ezetimibe
    CAS: 1376614-99-1

    ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe.