FGFR
FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.
Products Related to FGFR(109)
- GC73852Infigratinib-BocCAS: 2504949-83-9Purity: >98.00%
Infigratinib-Boc is a derivative of Infigratinib containing a Boc (t-Butyloxy carbonyl) group.
- GC74365VSPPLTLGQLLSCAS: 1206896-24-3Purity: >98.00%
VSPPLTLGQLLS is a small peptide FGFR3 inhibitor, peptide P3, inhibits FGFR3 phosphorylation.
- GC813192,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucroseCAS: 150302-84-4Purity: >98%
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica.
- GC81325VEGFR2-IN-84CAS: 861877-12-5Purity: >98%
VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold.
- GC81329TCB-32 hydrochlorideCAS: 169764-95-8Purity: >97.50%
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM.
- GN10527FormononetinCAS: 485-72-3Purity: >99.50%
Formononetin is a potent FGFR2 inhibitor with an IC 50 of 4.3μM. Formononetin potently inhibits angiogenesis and tumor growth.
- GN10540Fumalic acidCAS: 1135-24-6Purity: >99.00%
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC73852 | Infigratinib-Boc | 2504949-83-9 | >98.00% | |
Infigratinib-Boc is a derivative of Infigratinib containing a Boc (t-Butyloxy carbonyl) group. | ||||
| GC73947 | CEP-11981 | 856691-93-5 | >99.00% | |
CEP-11981(ESK981; BOL 303213X) is an orally active tyrosine kinase inhibitor (TKI), which can target TIE2, VEGFR1-3 and FGFR1, and has potential anti-tumor and anti-angiogenic effects. | ||||
| GC74046 | BR-cpd7 | - | >98.00% | |
BR-cpd7 is a PROTAC degrader for fibroblast growth factor receptor FGFR1/2 with DC50 of 10 nM. | ||||
| GC74365 | VSPPLTLGQLLS | 1206896-24-3 | >98.00% | |
VSPPLTLGQLLS is a small peptide FGFR3 inhibitor, peptide P3, inhibits FGFR3 phosphorylation. | ||||
| GC79483 | MD-3-A45 | 2314337-87-4 | >98.00% | |
MD-3-A45 is an inhibitor of fibroblast growth factor 23 ( FGF-23 ). | ||||
| GC81314 | OM-RCA-01 | - | >99.00% | |
OM-RCA-01 is an anti- FGFR1 monoclonal antibody with a K d of 1.59 nM for human FGFR1. | ||||
| GC81319 | 2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose | 150302-84-4 | >98% | |
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica. | ||||
| GC81324 | FGF7p | 2758194-43-1 | >99.00% | |
FGF7p is a small molecule peptide and a potential bladder protector. | ||||
| GC81325 | VEGFR2-IN-84 | 861877-12-5 | >98% | |
VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold. | ||||
| GC81329 | TCB-32 hydrochloride | 169764-95-8 | >97.50% | |
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM. | ||||
| GC91419 | CYY292 | 2644673-04-9 | >98.00% | |
CYY292 is an inhibitor of PDGFRα, PDGFRβ, FGFR1, -2, and -3, (IC50s = 5.35, 4.6, 28, 28, and 78 nM, respectively). | ||||
| GN10527 | Formononetin | 485-72-3 | >99.50% | |
Formononetin is a potent FGFR2 inhibitor with an IC 50 of 4.3μM. Formononetin potently inhibits angiogenesis and tumor growth. | ||||
| GN10540 | Fumalic acid | 1135-24-6 | >99.00% | |
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong. | ||||