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Home >> Signaling Pathways >> Microbiology & Virology >> Reverse Transcriptase

Reverse Transcriptase

Reverse transcriptase, also known as RNA-directed DNA polymerase catalyzes the transcription of RNA into DNA. It is key to the retroviruses infection.

Products for  Reverse Transcriptase

  1. Cat.No. Product Name Information
  2. GC33990 2,2'-Anhydrouridine (2,2'-Cyclouridine) 2,2'-Anhydrouridine (2,2'-Cyclouridine) is used for anticancer and antiviral research. 2,2'-Anhydrouridine (2,2'-Cyclouridine) Chemical Structure
  3. GC65085 3'-Azido-3'-deoxy-5-methylcytidine 3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells. 3'-Azido-3'-deoxy-5-methylcytidine Chemical Structure
  4. GC10387 3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt) Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. 3'-Azido-3'-deoxythymidine β-D-glucuronide (sodium salt) Chemical Structure
  5. GC35130 4'-Ethynyl-2'-deoxyadenosine 4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity. 4'-Ethynyl-2'-deoxyadenosine Chemical Structure
  6. GC13805 Abacavir Abacavir Chemical Structure
  7. GC11274 Abacavir sulfate Reverse transcriptase inhibitor Abacavir sulfate Chemical Structure
  8. GC46767 Abacavir-d4 An internal standard for the quantification of abacavir Abacavir-d4 Chemical Structure
  9. GC42731 Adefovir Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor. Adefovir Chemical Structure
  10. GC16841 Adefovir Dipivoxil Reverse transcriptase inhibitor Adefovir Dipivoxil Chemical Structure
  11. GC11744 AG 555 Potent EGFR-kinase inhibitor AG 555 Chemical Structure
  12. GC32381 BF738735 BF738735 is a phosphatidylinositol 4-kinase III beta (PI4KIIIβ) inhibitor with an IC50 of 5.7 nM. BF738735 Chemical Structure
  13. GC64261 Censavudine Censavudine (OBP-601; BMS-986001), a nucleoside analog, is a nucleoside reverse transcriptase inhibitor. Censavudine Chemical Structure
  14. GN10346 Corilagin

    A natural polyphenol

     Corilagin Chemical Structure
  15. GC35731 Corydine Corydine is a naturally occurring alkaloid which can be extracted from plants such as Croton echinocarpus leaves. Corydine Chemical Structure
  16. GN10072 Daidzin Daidzin Chemical Structure
  17. GC14452 Dapivirine (TMC120) Dapivirine (TMC120) (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) Chemical Structure
  18. GC35835 Delavirdine Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine Chemical Structure
  19. GC15452 Delavirdine mesylate Non-nucleoside reverse transcriptase inhibitor Delavirdine mesylate Chemical Structure
  20. GC64590 Dexelvucitabine Dexelvucitabine (Reverset; d-d4FC), a Cytidine analog, is an orally active nucleoside reverse transcriptase inhibitor. Dexelvucitabine Chemical Structure
  21. GC15330 Didanosine Reverse transcriptase inhibitor Didanosine Chemical Structure
  22. GC49022 Didanosine-d2 An internal standard for the quantification of didanosine Didanosine-d2 Chemical Structure
  23. GC19126 Doravirine Doravirine is a novel non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus (95% inhibitory concentration 19 nM, 50% human serum). Doravirine Chemical Structure
  24. GC12389 Efavirenz Reverse transcriptase inhibitor Efavirenz Chemical Structure
  25. GC62607 EFdA-TP tetraammonium EFdA-TP tetraammonium is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP tetraammonium Chemical Structure
  26. GC13653 Emtricitabine

    Reverse transcriptase inhibitor

     Emtricitabine Chemical Structure
  27. GC43600 Emtricitabine S-oxide Emtricitabine S-oxide is a potential impurity found in commercial preparations of emtricitabine. Emtricitabine S-oxide Chemical Structure
  28. GC16092 Entecavir Hydrate Entecavir Hydrate (BMS200475 monohydrate; SQ34676 monohydrate) is a potent and selective inhibitor of HBV, with an EC50 of 3.75 nM in HepG2 cell. Entecavir Hydrate Chemical Structure
  29. GC15996 Etravirine (TMC125) Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine (TMC125) Chemical Structure
  30. GC33536 Etravirine D4 (TMC-125 D4) Etravirine D4 (TMC-125 D4) (TMC-125 D4) is the deuterium labeled Etravirine. Etravirine D4 (TMC-125 D4) Chemical Structure
  31. GC45825 Etravirine-d6 An internal standard for the quantification of etravirine Etravirine-d6 Chemical Structure
  32. GC63541 FNC-TP

    FNC-TP is the intracellular active form of FNC.

     FNC-TP Chemical Structure
  33. GN10104 Gramine Gramine Chemical Structure
  34. GC12679 GS-7340 GS-7340 (GS-7340) is an investigational oral prodrug of Tenofovir. GS-7340 Chemical Structure
  35. GC32306 Islatravir (MK-8591) Islatravir (MK-8591) (MK-8591) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. Islatravir (MK-8591) Chemical Structure
  36. GC10317 Lamivudine Nucleoside analog reverse transcriptase inhibitor Lamivudine Chemical Structure
  37. GC16596 Lersivirine An NNRTI Lersivirine Chemical Structure
  38. GC32358 Loviride (R 89439) Loviride (R 89439) (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 μM for reverse transcriptase from HIV-1. Loviride (R 89439) Chemical Structure
  39. GC16387 Nevirapine Non-nucleoside reverse transcriptase inhibitor Nevirapine Chemical Structure
  40. GC47770 Nevirapine-d4 An internal standard for the quantification of nevirapine Nevirapine-d4 Chemical Structure
  41. GC61134 Nigranoic acid Nigranoic acid is a triterpenoid separated from Schisandra chinensis. Nigranoic acid Chemical Structure
  42. GC10084 Pyridoxal 5 phosphate Pyridoxal 5 phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia. Pyridoxal 5 phosphate Chemical Structure
  43. GC65207 R-10015 R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1. R-10015 Chemical Structure
  44. GC11059 Rilpivirine A non-nucleoside reverse transcriptase inhibitor Rilpivirine Chemical Structure
  45. GC25867 Rilpivirine Hydrochloride Rilpivirine (TMC278), is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. Rilpivirine Hydrochloride Chemical Structure
  46. GC62223 Ro-0335 RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates. Ro-0335 Chemical Structure
  47. GC37674 SPK-601 SPK-601 (LMV-601) is an inhibitor of the phosphatidylcholine-specific phospholipase C (PC-PLC). SPK-601 Chemical Structure
  48. GC63486 Stampidine Stampidine is a nucleoside reverse transcriptase inhibitor (NRTI) with potent and broad-spectrum anti-HIV activity. Stampidine Chemical Structure
  49. GC12830 Stavudine (d4T) Stavudine (d4T) (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine (d4T) Chemical Structure
  50. GC37690 Stavudine sodium Stavudine (d4T) sodium is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Stavudine sodium Chemical Structure
  51. GC12125 Tenofovir

    HIV reverse transcriptase inhibitor

     Tenofovir Chemical Structure
  52. GC37758 Tenofovir alafenamide fumarate Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral prodrug of Tenofovir. Tenofovir alafenamide fumarate Chemical Structure
  53. GC37759 Tenofovir alafenamide hemifumarate Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral prodrug of Tenofovir. Tenofovir alafenamide hemifumarate Chemical Structure
  54. GC60357 Tenofovir diphosphate Tenofovir diphosphate (TFV-DP) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT). Tenofovir diphosphate Chemical Structure
  55. GC60358 Tenofovir diphosphate triethylamine Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT). Tenofovir diphosphate triethylamine Chemical Structure
  56. GC37760 Tenofovir Disoproxil Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. Tenofovir Disoproxil Chemical Structure
  57. GC15067 Tenofovir Disoproxil Fumarate Antiretroviral agent( HIV-1 RT inhibitor) Tenofovir Disoproxil Fumarate Chemical Structure
  58. GC13846 Tenofovir hydrate Reverse transcriptase inhibitor Tenofovir hydrate Chemical Structure
  59. GC15488 Tenofovir maleate Reverse transcriptase inhibitor Tenofovir maleate Chemical Structure
  60. GC70089 Ulonivirine

    Ulonivirine (MK-8507) is an orally active non-nucleoside reverse transcriptase inhibitor with high antiviral activity. It can be used for research on HIV-1 infection.

     Ulonivirine Chemical Structure
  61. GC14720 Zalcitabine Reverse transcriptase inhibitor Zalcitabine Chemical Structure

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