Reverse Transcriptase

EFdA-TP tetraammonium is a potent nucleoside reverse transcriptase (RT) inhibitor.

Stampidine is a nucleoside reverse transcriptase inhibitor (NRTI) with potent and broad-spectrum anti-HIV activity.

FNC-TP is the intracellular active form of FNC.

Censavudine (OBP-601; BMS-986001), a nucleoside analog, is a nucleoside reverse transcriptase inhibitor.

Dexelvucitabine (Reverset; d-d4FC), a Cytidine analog, is an orally active nucleoside reverse transcriptase inhibitor.

3'-Azido-3'-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 μM in MCF-7 cells.

R-10015, a broad-spectrum antiviral compound for HIV infection, acts as a potent and selective inhibitor of LIM domain kinase (LIMK) and binds to the ATP-binding pocket, with an IC50 of 38 nM for human LIMK1.

Ulonivirine (MK-8507) is an orally active non-nucleoside reverse transcriptase inhibitor with high antiviral activity. It can be used for research on HIV-1 infection.

EFdA-TP tetralithium is a potent nucleoside reverse transcriptase (RT) inhibitor.

(Rac)-Emtricitabine S-oxide ((Rac)-Emtricitabine sulfoxide; (Rac)-Emtricitabine Degradant-III) is Emtricitabine S-oxide racemic modification.

Lamivudine triphosphate (3TCTP) TEA is a phosphorylated Lamivudine (a nucleoside analogue).

Gramine-d 2 is the deuterium labeled Gramine [1] . Gramine (Donaxine) is a natural alkaloid isolated from giant reed [2] , acts as an active adiponectin receptor (AdipoR) agonist, with IC 50 s of 3.2 and 4.2 μM for AdipoR2 and AdipoR1, respectively [2] . Gramine is also a human and mouse β2-Adrenergic receptor (β2-AR) agonist [3] . Gramine (Donaxine) has anti-tumor, anti-viral and anti-inflammatory properties [2] .

An Akt activation inhibitor and active metabolite of triciribine

A reverse transcriptase inhibitor and an active metabolite of ddA and ddI

Corilagin, a natural plant polyphenol tannic acid, is a potent inhibitor of the binding of SARS CoV-2 spike protein RBD to host receptor angiotensin-converting enzyme 2 (ACE2), with an IC 50 value of 5.5μM.

Lamivudine is an oral nucleoside analogue, which acts as the nucleoside reverse transcriptase inhibitor, with an EC 50 of 0.07±0.02μg/ml for anti-hepatitis B virus (HBV) activity.

Non-nucleoside reverse transcriptase inhibitor

Reverse transcriptase inhibitor

Reverse transcriptase inhibitor