GLPBio

Mefuparib

Catalog No.: GC83532Purity:>99.50%Synonyms: CVL218
COASDSData Sheet
Mefuparib (CVL218) is a poly ADP-ribose polymerase ( PARP ) inhibitor used in cancer research that exhibits potent brain penetration due to its high protein binding.

Los productos son exclusivamente para uso en investigación. No aptos para uso humano. No vendemos a pacientes.

Mefuparib
Cas No.: 1392502-82-7
10mM (in 1mL DMSO)In Stock
$103.00
1
5mgIn Stock
$94.00
1
10mgIn Stock
$151.00
1
25mgIn Stock
$301.00
1
50mgIn Stock
$482.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citas (Citations)

Actualmente no hay citas disponibles para este producto. A continuación se muestran publicaciones seleccionadas que citan productos GlpBio.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Descripción (Description)

Mefuparib (CVL218) is a poly ADP-ribose polymerase ( PARP ) inhibitor used in cancer research that exhibits potent brain penetration due to its high protein binding.

References:
[1]. Absorption, distribution, metabolism, and excretion of [14C]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats

Documentos del producto (Product Documents)

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Propiedades químicas (Chemical Properties)

N.º CAS
1392502-82-7
Sinónimos
CVL218
Fórmula molecular
C17H15FN2O2
Peso molecular
298.31
Solubilidad
DMSO: 6.25 mg/mL (20.95 mM; ultrasonic and warming and heat to 60°C)
Almacenamiento
Store at -20°C
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.

Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad

g/mol

Reviews

Review for Mefuparib

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