MPT0B390 |
Catalog No.GC64729 |
MPT0B390 es un derivado basado en arilsulfonamida con una potente capacidad inhibidora de HDAC. MPT0B390, inductor de TIMP3, inhibe el crecimiento tumoral, la metÁstasis y la angiogénesis. MPT0B390 muestra actividad antiproliferativa contra la lÍnea celular de cÁncer de colon humano HCT116 con un GI50 de 0,03 μM.
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Cas No.: 1817802-18-8
Sample solution is provided at 25 µL, 10mM.
MPT0B390 is an arylsulfonamide-based derivative with potent HDAC inhibitory ability. MPT0B390, TIMP3 inducer, inhibits tumor growth, metastasis and angiogenesis. MPT0B390 shows antiproliferative activity against human colon cancer cell line HCT116 with the GI50 of 0.03 μM[1].
[1]. Han-Li Huang, et al. TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis. Theranostics. 2019 Sep 18;9(22):6676-6689.
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