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Stem Cell

Research Areas

Products Related to Stem Cell(471)

  • GC43809 structure
    GC43809Hedgehog Antagonist VIII
    CAS: 330796-24-2
    Purity: >98.00%

    Hedgehog (Hh) proteins, important regulators of development, bind the cell-surface protein Patched, allowing activation of Smoothened.

  • GC43847 structure
    GC43847Histone H3K27Me2 (21-44)-GK-biotin (trifluoroacetate salt)
    Purity: >95.00%

    Histone H3K27Me2 (21-44)-GK-biotin is a peptide fragment of histone H3 that corresponds to amino acid residues 22-45 of the human histone H3.1 and 3.2 sequences.

  • GC43848 structure
    GC43848Histone H3K27Me2 (23-34) (trifluoroacetate salt)
    Purity: >95.00%

    Histone H3K27Me2 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences.

  • GC43873 structure
    GC43873Hydrocortisone 21-hemisuccinate (sodium salt)
    CAS: 125-04-2
    Purity: >98.00%

    Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol.

  • GC44080 structure
    GC44080LLP-3
    CAS: 1453835-43-2
    Purity: >95.00%

    LLP-3 es un potente inhibidor de Survivin que interrumpe la interacciÓn Survivin-Ran en las células cancerosas. LLP-3 se puede utilizar en la investigaciÓn de Glioblastoma multiforme (GBM).

  • GC44213 structure
    GC44213ML115
    CAS: 912798-42-6
    Purity: >98.00%

    Signal transducer and activator of transcription 3 (STAT3) is a cytokine-inducible transcription factor with roles in inflammation and cancer.

  • GC44245 structure
    GC44245MoTP
    CAS: 57055-82-0
    Purity: >98.00%

    MoTP es un antagonista especÍfico del receptor del factor activador de plaquetas y puede inducir la ablaciÓn de melanocitos. MoTP se puede utilizar para la investigaciÓn del cÁncer.

  • GC44250 structure
    GC44250MS351
    CAS: 472984-79-5
    Purity: >98.00%

    MS351 is an antagonist of chromobox 7 (CBX7) that acts by binding the CBX7 chromodomain.

  • GC44321 structure
    GC44321Nat-20(S)-yne
    CAS: 1397692-46-4
    Purity: >90.00%

    Smoothened (SMO) is a GPCR-like receptor which, with Patched, mediates hedgehog signaling to regulate gene expression through the Gli transcription factors.

  • GC44458 structure
    GC44458N-Palmitoyl-L-Aspartate
    CAS: 1782-17-8
    Purity: >98.00%

    N-Palmitoyl-L-aspartate is a natural N-acylaspartate that inhibits Hedgehog signaling after stimulation with Smoothened agonist or non-sterol-modified Sonic Hedgehog.

  • GC44467 structure
    GC44467NSC 668036
    CAS: 144678-63-7
    Purity: >98.00%

    NSC 668036 es un inhibidor del dominio PDZ Disheveled (Dvl) con una Kd de 237 µM.

  • GC44612 structure
    GC44612PF-4800567
    CAS: 1188296-52-7
    Purity: >98.00%

    PF-4800567 es un inhibidor potente y selectivo de la caseÍna quinasa 1ε (CK1ε), con una IC50 de 32 nM, que es mÁs de 20 veces mÁs selectiva que la CK1δ (IC50, 711 nM).

  • GC44851 structure
    GC44851Rosiglitazone (potassium salt)
    CAS: 316371-84-3
    Purity: >98.00%

    La rosiglitazona (BRL 49653) potÁsica es un PPARγ selectivo activo por vÍa oral; agonista (EC50: 60 nM, Kd: 40 nM).

  • GC44855 structure
    GC44855RU-SKI 43 (hydrochloride)
    CAS: 1782573-67-4
    Purity: >98.50%

    RU-SKI 43 (clorhidrato) es un inhibidor potente y selectivo de Hedgehog aciltransferasa (Hhat) con una IC50 de 850 nM. RU-SKI 43 (clorhidrato) reduce la activación de Gli-1 a través de la señalización no canónica independiente de Smoothened y disminuye la actividad de las vías Akt y mTOR. RU-SKI 43 (clorhidrato) tiene actividad anticancerígena.

  • GC45090 structure
    GC45090Triparanol
    CAS: 78-41-1
    Purity: >98.00%

    Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol.

  • GC45137 structure
    GC45137Valproic Acid Acyl-D-Glucuronide
    Purity: >95.00%

    Valproic acid acyl-D-glucuronide is the major urinary metabolite of valproic acid.

  • GC45354 structure
    GC453544β-Hydroxywithanolide E
    CAS: 54334-04-2
    Purity: >95.00%

    4β-Hydroxywithanolide E, aislado de Physalis peruviana L.

  • GC45482 structure
    GC45482Histone H3K9Me1 (3-17) (human, mouse, rat, porcine, bovine) (trifluoroacetate salt)
    Purity: >95.00%

  • GC45596 structure
    GC45596YW1128
    CAS: 2131223-64-6
    Purity: >98.00%

    YW1128 (compuesto 3a) es un potente inhibidor de Wnt/β-catenina.

  • GC45597 structure
    GC45597YW1159
    CAS: 2131223-69-1
    Purity: >98.00%

  • GC46015 structure
    GC46015KY 05009
    CAS: 1228280-29-2
    Purity: >99.50%

    KY 05009 es un inhibidor de la cinasa que interactúa con Nck y Traf2 competitivo con ATP (TNIK) con una Ki de 100 nM. KY 05009 inhibe farmacológicamente la transición epitelial a mesenquimatosa (EMT) inducida por TGF-β1 en células de adenocarcinoma de pulmón humano. KY 05009 inhibe la expresión proteica de TNIK y la actividad transcripcional de los genes diana Wnt e induce la apoptosis en las células cancerosas. KY 05009 ejerce actividad anticancerígena.

  • GC46939 structure
    GC46939BODIPY-aminoacetaldehyde diethyl acetal
    CAS: 247069-93-8
    Purity: >98.00%

    BODIPY-aminoacetaldehyde diethyl acetal (BAAA-DA) es un precursor estable de BODIPY-aminoacetaldehído (BAAA), un sustrato fluorescente permeable a células para la deshidrogenasa de aldehídos (ALDH) con un Ex/Em de 488/512nm.

  • GC46947 structure
    GC46947BRD-K4477
    CAS: 2719-05-3
    Purity: >98.00%

    A small molecule promotor of hepatocyte differentiation

  • GC46986 structure
    GC46986C18 Ceramide-1-phosphate-d3 (d18:1/18:0-d3)
    CAS: 2692624-25-0
    Purity: >99.00%

    A neuropeptide with diverse biological activities