GLPBio

Telomerase

Telomerase is a ribonucleoprotein polymerase that adds telomere repeat TTAGGG to maintain telomere ends. It plays roles in senescence, oncogenesis, chromosomal repair, aging and antiapoptosis etc.

Products Related to Telomerase(15)

  • GC13636 structure
    GC13636BIBR 1532
    CAS: 321674-73-1
    Purity: >99.50%

    BIBR 1532 is a potent small molecule inhibitor of human telomerase, with an IC 50 value of 5μM for telomerase inhibition. BIBR 1532 causes telomeres to shorten and reduces tumor cell proliferation.

  • GC10115 structure
    GC10115360A iodide
    CAS: 737763-37-0
    Purity: >98.00%

    360A iodide is a G-quadruplex stabilizer and also an effective inhibitor of telomerase activity (IC₅₀=300nM).

  • GC12092 structure
    GC12092TMPyP4 tosylate
    CAS: 36951-72-1
    Purity: >95.00%

    TMPyP4 tosylate is a quadruplex-specific ligand that can inhibit the interaction between G-quadruplexes and Insulin-like growth factor type I (IGF-1).

  • GC12193 structure
    GC121936-Thio-dG
    CAS: 789-61-7
    Purity: >98.00%

    6-Thio-dG is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.

  • GC15389 structure
    GC15389360A
    CAS: 794458-56-3
    Purity: >98%
  • GC16116 structure
    GC16116Costunolide
    CAS: 553-21-9
    Purity: >98.00%

    Costunolide is a multi-target NF-κB inhibitor with diverse biological activities.

  • GC16485 structure
    GC16485RHPS4
    CAS: 390362-78-4
    Purity: >98.50%

    Telomerase inhibitor

  • GC38102 structure
    GC38102Epithalon
    CAS: 307297-39-8
    Purity: >98%

    Epithalon is a tetrapeptide that induces telomerase activity and telomere elongation.

  • GC38103 structure
    GC38103Epithalon TFA
    CAS: 307297-39-8
    Purity: >98.00%

    Epitalon TFA is an anti-aging agent and a telomerase activator.

  • GC38858 structure
    GC38858Telomerase-IN-2
    CAS: 1610878-54-0
    Purity: >98.50%

    Telomerase-IN-2 is a telomerase inhibitor, and inhibits telomerase activity by decreasing expression of dyskerin, with an IC50 of 0.89??M. Anti-cancer activity.

  • GC39484 structure
    GC39484Ceramides Mixture
    CAS: 100403-19-8
    Purity: >98.00%

    Ceramides Mixture is a main lipid component of the permeability barrier in the epidermis, where it plays a crucial role in maintaining skin integrity and barrier function.

  • GC61513 structure
    GC61513Epitalon TFA
    Purity: >99.00%

    Epitalon TFA is an anti-aging agent and a telomerase activator.

  • GC64073 structure
    GC64073Telomerase-IN-3
    CAS: 150096-77-8
    Purity: >98%

    Telomerase-IN-3 is a telomerase inhibitor, which directly targets hTERT promoter activity. hTERT is the key component for maintenance of telomerase activity.

  • GC73158 structure
    GC73158L2H2-6OTD diformic
    Purity: >99.00%

    L2H2-6OTD acetate contains one to four G-quadruplex binding loops and is a telomere inhibitor analog.

  • GC74148 structure
    GC74148L2H2-6OTD intermediate-2
    CAS: 890403-75-5
    Purity: >99.00%

    L2H2-6OTD intermediate-2 is an intermediate of telomerase inhibitor, which can be used in the synthesis of ADC.