FGFR
FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.
Products Related to FGFR(109)
- GC73852Infigratinib-BocCAS: 2504949-83-9Purity: >98.00%
Infigratinib-Boc هو مشتق من Infigratinib يحتوي على مجموعة Boc (t-Butyloxy carbonyl).
- GC74365VSPPLTLGQLLSCAS: 1206896-24-3Purity: >98.00%
VSPPLTLGQLLS هو مثبط ببتيد صغير FGFR3، ببتيد P3، يمنع فسفرة FGFR3.
- GC813192,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucroseCAS: 150302-84-4Purity: >98%
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica.
- GC81325VEGFR2-IN-84CAS: 861877-12-5Purity: >98%
VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold.
- GC81329TCB-32 hydrochlorideCAS: 169764-95-8Purity: >97.50%
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM.
- GN10527FormononetinCAS: 485-72-3Purity: >99.50%
Formononetin is a potent FGFR2 inhibitor with an IC 50 of 4.3μM. Formononetin potently inhibits angiogenesis and tumor growth.
- GN10540Fumalic acidCAS: 1135-24-6Purity: >99.00%
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC73852 | Infigratinib-Boc | 2504949-83-9 | >98.00% | |
Infigratinib-Boc هو مشتق من Infigratinib يحتوي على مجموعة Boc (t-Butyloxy carbonyl). | ||||
| GC73947 | CEP-11981 | 856691-93-5 | >99.00% | |
CEP-11981(ESK981; BOL 303213X) هو مثبط تيروزين كيناز نشط عن طريق الفم (TKI)، والذي يمكن أن يستهدف TIE2، VEGFR1-3 و FGFR1، وله تأثيرات محتملة مضادة للورم ومضادة لتولد الأوعية. | ||||
| GC74046 | BR-cpd7 | - | >98.00% | |
أما BR-cpd7 فهو محلل بروتاك لمستقبل عامل نمو الأرومة الليفية FGFR1/2 مع DC50 قدره 10 نانومتر. | ||||
| GC74365 | VSPPLTLGQLLS | 1206896-24-3 | >98.00% | |
VSPPLTLGQLLS هو مثبط ببتيد صغير FGFR3، ببتيد P3، يمنع فسفرة FGFR3. | ||||
| GC79483 | MD-3-A45 | 2314337-87-4 | >98.00% | |
MD-3-A45 is an inhibitor of fibroblast growth factor 23 ( FGF-23 ). | ||||
| GC81314 | OM-RCA-01 | - | >99.00% | |
OM-RCA-01 is an anti- FGFR1 monoclonal antibody with a K d of 1.59 nM for human FGFR1. | ||||
| GC81319 | 2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose | 150302-84-4 | >98% | |
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica. | ||||
| GC81324 | FGF7p | 2758194-43-1 | >99.00% | |
FGF7p is a small molecule peptide and a potential bladder protector. | ||||
| GC81325 | VEGFR2-IN-84 | 861877-12-5 | >98% | |
VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold. | ||||
| GC81329 | TCB-32 hydrochloride | 169764-95-8 | >97.50% | |
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM. | ||||
| GC91419 | CYY292 | 2644673-04-9 | >98.00% | |
CYY292 هو مثبط لـ PDGFRα و PDGFRβ و FGFR1، -2، و-3 (IC50s = 5.35 و 4.6 و 28 و 28 و 78 نانومتر على التوالي). | ||||
| GN10527 | Formononetin | 485-72-3 | >99.50% | |
Formononetin is a potent FGFR2 inhibitor with an IC 50 of 4.3μM. Formononetin potently inhibits angiogenesis and tumor growth. | ||||
| GN10540 | Fumalic acid | 1135-24-6 | >99.00% | |
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong. | ||||