Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits leukocyte activation and induces phase II enzymes during the initiation phase of carcinogenesis. When examined for its potential use in Alzheimer's disease treatment, auraptene was shown to inhibit β-secretase (BACE1) activity with an IC50 value of 345.1 μM.
Auraptene
Catalog No.: GC42873Purity:>99.50%Synonyms: 7Geranyloxycoumarin
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7.
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Cas No.: 495-02-3
5mgIn Stock
$45.00
1
10mgIn Stock
$60.00
1
25mgIn Stock
$105.00
1
50mgIn Stock
$187.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5mg | $45.00 | In Stock | 1 | |
| 10mg | $60.00 | In Stock | 1 | |
| 25mg | $105.00 | In Stock | 1 | |
| 50mg | $187.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>99.50%Appearance:A solid
Chemical Properties
CAS No.
495-02-3
Synonyms
7Geranyloxycoumarin
SMILES
O=C1C=CC2=C(C=C(OC/C=C(C)/CC/C=C(C)\C)C=C2)O1
Molecular Formula
C19H22O3
Molecular Weight
298.4
Solubility
DMF: 14 mg/ml,DMF:PBS(pH7.2) (1:2): 0.3 mg/ml,DMSO: 12 mg/ml,Ethanol: 12 mg/ml
Storage
4°C, protect from light
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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