AZD4573 is a CDK9 inhibitor with an IC50 of <3 nM extracted from patent US 20160376287 A1, example 14.
[1]. Bernard Barlaam, et al. Chemical Compounds. US 20160376287 A1.
AZD4573
Catalog No.: GC32717Purity:>99.50%
AZD4573 is a potent and highly selective CDK9 inhibitor (IC50 of <4 nM) that enables transient target engagement for the treatment of hematologic malignancies.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2057509-72-3
10mM (in 1mL DMSO)In Stock
$148.00
1
1mgIn Stock
$60.00
1
5mgIn Stock
$135.00
1
10mgIn Stock
$216.00
1
25mgIn Stock
$356.00
1
50mgIn Stock
$499.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $148.00 | In Stock | 1 | |
| 1mg | $60.00 | In Stock | 1 | |
| 5mg | $135.00 | In Stock | 1 | |
| 10mg | $216.00 | In Stock | 1 | |
| 25mg | $356.00 | In Stock | 1 | |
| 50mg | $499.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>99.50%Appearance:A solid
Chemical Properties
CAS No.
2057509-72-3
SMILES
ClC1=CN=C(NC([C@H]2CCC[C@@H](NC(C)=O)C2)=O)C=C1C3=C(CC(C)(C)C4)N4N=C3
Molecular Formula
C22H28ClN5O2
Molecular Weight
429.94
Solubility
DMSO : ≥ 125 mg/mL (290.74 mM)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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