CAY10684 |
| Catalog No.GC43191 |
Prostaglandin E2 activates four E prostanoid (EP) receptors, EP1-4.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 493035-81-7
Sample solution is provided at 25 µL, 10mM.
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Prostaglandin E2 activates four E prostanoid (EP) receptors, EP1-4. EP4 is a G protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10684 is a lactam that acts as a potent EP4 agonist, triggering cAMP signaling with an EC50 value of 0.8 nM. It displays more than 1,000-fold selectivity for EP4 over other EP receptors.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
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