BAY-524 |
Katalog-Nr.GC33236 |
BAY-524 ist ein potenter Bub1-Kinase-Inhibitor. BAY-524 hemmt die rekombinante katalytische DomÄne von humanem Bub1 mit einem IC50 von 450 nM. BAY-524 kann in Kombination mit anderen Wirkstoffen fÜr die Krebsforschung eingesetzt werden.
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Cas No.: 1445830-39-6
Sample solution is provided at 25 µL, 10mM.
BAY-524 is a Bub1 inhibitor, with an IC50 of 450 nM for human Bub1 in the presence of 2 mM ATP.
[1]. Baron AP, et al. Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. Elife. 2016 Feb 17;5. pii: e12187.
Average Rating: 5
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