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Thalidomide-NH-C6-NH2 TFA

Katalog-Nr.GC39513

Thalidomide-NH-C6-NH2 TFA ist ein synthetisiertes E3-Ligase-Ligand-Linker-Konjugat, das den auf Thalidomid basierenden Cereblon-Liganden und einen in der PROTAC-Technologie verwendeten Linker enthÄlt.

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Thalidomide-NH-C6-NH2 TFA Chemische Struktur

Cas No.: 2093386-51-5

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

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