Cardiovascular
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Cardiovascular
The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.
Research Areas
- Acute Phase Reactants(15)
- Angina(14)
- Arrhythmia(82)
- Atherosclerosis(88)
- Chronic Kidney Disease(18)
- Coagulation & Hemostasis(124)
- Coronary Artery Disease(7)
- Diabetic Nephropathy(8)
- Endothelium(33)
- Erythrocytes & Hemoglobin(49)
- Heart Failure(33)
- Hypertension(162)
- Hypotension(24)
- Lipoproteins(61)
- Myocardial Contractility(33)
- Myocardial Hypertrophy(21)
- Myocardial Infarction(61)
- Others(1)
- Serum Proteins(11)
- Smooth Muscle Cells(36)
- Storage & Transport(6)
- Stroke(48)
- Thrombosis(52)
- Vasoconstriction(59)
- Vasodilation(141)
- Cardiomyopathy(5)
- Cholesterol Metabolism(44)
Products Related to Cardiovascular(821)
- GC43745Geranyl Pyrophosphate (triammonium salt)CAS: 116057-55-7Purity: >95.00%
Geranylpyrophosphat (Triammoniumsalz) ist ein wichtiger Zwischenstoff im Isoprenoid-Biosyntheseweg (IBP).
- GC43802HA-1004 (hydrochloride)CAS: 92564-08-4Purity: >98.00%
HA-1004 is an inhibitor of protein kinase G (PKG) and PKA (Kis = 1.4 and 2.3 μM, respectively).
- GC43803HA-1077 (hydrochloride)CAS: 203911-27-7Purity: >98.00%
Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μ ;M, 1.650 μM fÜr ROCK2 bzw. PKA, PKC, PKG. HA-1077 (Hydrochlorid) ist auch ein potenter Ca2+-Kanalantagonist und Vasodilatator.
- GC43869Homovanillic Acid sulfate (sodium salt)Purity: >98.00%
Homovanillic acid sulfate is a phenol found in olive oil and a dopamine metabolite.
- GC43883HymeglusinCAS: 29066-42-0Purity: >95.00%
Hymeglusin ist als Pilz-β-Lacton-Antibiotikum ein HMG-CoA-Synthase-Inhibitor (IC50 = 0,12 μM).
- GC43890ICI 216140CAS: 124001-41-8Purity: >95.00%
Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity.
- GC44062L-hydroxy Arginine (acetate)CAS: 1140844-61-6Purity: >95.00%
L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide.
- GC44155Menaquinone 9CAS: 523-39-7Purity: >98.00%
Menaquinon 9 (MK-9) ist ein Vitamin-K2-Analogon, das in verschiedenen Bakterien gefunden wurde, einschließlich E.
- GC44180Methylcarbamyl PAF C-16CAS: 91575-58-5Purity: >98.00%
Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH.
- GC44181Methylcarbamyl PAF C-8Purity: >98.00%
Methylcarbamyl PAF C-8 is the C-8 analog of Methylcarbamyl PAF C-16.
- GC44320N-Arachidonoyl-L-SerineCAS: 187224-29-9Purity: >98.00%
Arachidonoyl amides of both amino acids and neurotransmitters such as dopamine have been previously reported in the literature.
- GC44345N-Desethyl VardenafilCAS: 448184-46-1Purity: >98.00%
N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5.
- GC44350N-Desmethyl SildenafilCAS: 139755-82-1Purity: >98.00%
N-Desmethyl Sildenafil (Desmethylsildenafil) ist ein Hauptmetabolit von Sildenafil.
- GC44351N-Desmethyl Sildenafil (citrate)Purity: >98.00%
N-Desmethyl sildenafil is a major metabolite of sildenafil.
- GC44358Nebivolol O-β-D-GlucuronidePurity: >95.00%
Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC43745 | Geranyl Pyrophosphate (triammonium salt) | 116057-55-7 | >95.00% | |
Geranylpyrophosphat (Triammoniumsalz) ist ein wichtiger Zwischenstoff im Isoprenoid-Biosyntheseweg (IBP). | ||||
| GC43800 | GW 9578 | 247923-29-1 | >98.00% | |
GW9578 ist ein Subtyp-selektiver PPARα-Agonist (EC50s von 5 und 50 nM fÜr murines und humanes PPAR-α) mit starker lipidsenkender AktivitÄt. | ||||
| GC43802 | HA-1004 (hydrochloride) | 92564-08-4 | >98.00% | |
HA-1004 is an inhibitor of protein kinase G (PKG) and PKA (Kis = 1.4 and 2.3 μM, respectively). | ||||
| GC43803 | HA-1077 (hydrochloride) | 203911-27-7 | >98.00% | |
Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μ ;M, 1.650 μM fÜr ROCK2 bzw. PKA, PKC, PKG. HA-1077 (Hydrochlorid) ist auch ein potenter Ca2+-Kanalantagonist und Vasodilatator. | ||||
| GC43869 | Homovanillic Acid sulfate (sodium salt) | - | >98.00% | |
Homovanillic acid sulfate is a phenol found in olive oil and a dopamine metabolite. | ||||
| GC43883 | Hymeglusin | 29066-42-0 | >95.00% | |
Hymeglusin ist als Pilz-β-Lacton-Antibiotikum ein HMG-CoA-Synthase-Inhibitor (IC50 = 0,12 μM). | ||||
| GC43890 | ICI 216140 | 124001-41-8 | >95.00% | |
Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity. | ||||
| GC43910 | I-SAP | 133538-58-6 | >98.00% | |
I-SAP is a high affinity TP receptor antagonist. | ||||
| GC43997 | KDdiA-PC | 439904-34-4 | >98.00% | |
KDdiA-PC ist eine Art oxidiertes LDL (oxLDL) und ein Ligand fÜr den Makrophagen-Scavenger-Rezeptor CD36. | ||||
| GC44011 | KOdiA-PC | 439904-33-3 | >98.00% | |
Oxidized low-density lipoprotien (oxLDL) particles contain low molecular weight species which are cytotoxic and pro-atherogenic. | ||||
| GC44013 | KR-32568 | 852146-73-7 | >98.00% | |
KR-32568 is an inhibitor of the sodium-hydrogen exchanger isoform-1 (NHE-1; IC50 = 230 nM). | ||||
| GC44062 | L-hydroxy Arginine (acetate) | 1140844-61-6 | >95.00% | |
L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. | ||||
| GC44093 | Lutein | 127-40-2 | >98.00% | |
Lutein is a naturally occurring carotenoid with multiple biological activities and is widely found in green leafy vegetables, corn, and egg yolks. | ||||
| GC44112 | Mabuterol | 56341-08-3 | >98.00% | |
Mabuterol is an agonist of the β2-adrenergic receptor (β2-AR). | ||||
| GC44155 | Menaquinone 9 | 523-39-7 | >98.00% | |
Menaquinon 9 (MK-9) ist ein Vitamin-K2-Analogon, das in verschiedenen Bakterien gefunden wurde, einschließlich E. | ||||
| GC44170 | Metaraminol (tartrate) | 33402-03-8 | >98.00% | |
Metaraminol is a vasoconstrictor. | ||||
| GC44180 | Methylcarbamyl PAF C-16 | 91575-58-5 | >98.00% | |
Methylcarbamyl PAF C-16 is a stable analog of PAF C-16 with a half-life greater than 100 minutes in platelet poor plasma due to its resistance to degradation by PAF-AH. | ||||
| GC44181 | Methylcarbamyl PAF C-8 | - | >98.00% | |
Methylcarbamyl PAF C-8 is the C-8 analog of Methylcarbamyl PAF C-16. | ||||
| GC44198 | MitoA | - | >95.00% | |
MitoA is a ratiometric mass spectrometry probe that can be used for assessing changes in H2S within mitochondria in vivo. | ||||
| GC44320 | N-Arachidonoyl-L-Serine | 187224-29-9 | >98.00% | |
Arachidonoyl amides of both amino acids and neurotransmitters such as dopamine have been previously reported in the literature. | ||||
| GC44345 | N-Desethyl Vardenafil | 448184-46-1 | >98.00% | |
N-Desethyl vardenafil is a metabolite of vardenafil , a phosphodiesterase 5 inhibitor, that is formed by the action of cytochrome P450 (CYP)3A4 and CYP3A5. | ||||
| GC44350 | N-Desmethyl Sildenafil | 139755-82-1 | >98.00% | |
N-Desmethyl Sildenafil (Desmethylsildenafil) ist ein Hauptmetabolit von Sildenafil. | ||||
| GC44351 | N-Desmethyl Sildenafil (citrate) | - | >98.00% | |
N-Desmethyl sildenafil is a major metabolite of sildenafil. | ||||
| GC44358 | Nebivolol O-β-D-Glucuronide | - | >95.00% | |
Nebivolol O-β-D-glucuronide is an active metabolite of the β1-adrenergic receptor antagonist nebivolol. | ||||