Cardiovascular

Prostacyclin (PGI2) is a cyclooxygenase metabolite with antithrombotic properties found in vascular endothelial cells.

Chloramphenicol succinate is a water-soluble prodrug form of the antibiotic chloramphenicol.

Chlorthalidone impurity G is a potential impurity found in commercial preparations of chlorthalidone that has moderate antihypertensive effects.

Cholesteryl arachidonate is a cholesterol ester that is found in plasma and the adrenal gland.

Cholesteryl linoleate hydroperoxides are derived from the autoxidation of cholesteryl linoleate and contain a mixture of racemic 9- and 13-HpODE cholesteryl esters.

Cholesteryl stearate is a cholesterol ester.

Ciprostene is the 9β-methyl analog of carbaprostacyclin and a stable analog of PGI2.

Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM).

C-Type natriuretic peptide-22 (CNP-22) is an endogenous peptide with diverse biological activities.

CV-6209 (Chlorid) ist ein potenter Antagonist des Thrombozytenaktivierungsfaktors (PAF).

Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran.

Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine.

Dehydroevodiamine is an alkaloid that has been isolated from E.

Diallyldisulfid hemmt die humane Squalenmonooxygenase mit einem IC50 von 400 μM fÜr die Squalenepoxidation.

Hydrogen sulphide (H2S), a naturally occurring gasotransmitter, is a potent vasodilator and pro-inflammatory mediator.

Doxorubicinol is the major metabolite of doxorubicin, an anthracycline antitumor antibiotic that inhibits DNA topoisomerase II by inducing double-stranded DNA breaks.

DPPP (DPPP) ist eine reaktive Sonde mit fluorogenem Peroxid.

Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II, a peptide hormone that impacts vascular smooth muscle tone and renal salt exchange, driving hypertension.

Endothelin-1 is a peptide vasoconstrictor and agonist of endothelin (ET) receptors ETA and ETB (IC50s = 0.15 and 0.12 nM, respectively).

Endothelin-2 is a peptide vasoconstrictor and ligand for the endothelin (ET) receptors ETA and ETB (Kbs= 32.8 and 1.33 nM, respectively).

Endothelin-3 is a peptide vasoconstricter and a ligand of the endothelin (ET) receptors ETA and ETB (Kbs = 1.05 and 1.49, respectively).

Ezetimibe hydroxy glucuronide is a minor phase II glucuronide metabolite of ezetimibe .

Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver.

Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation.