Cardiovascular
Cardiovascular
The cardiovascular system consists of the heart, blood and blood vessels. These organs form the 3 major closed circulation systems in the body, i.e., the pulmonary, coronary and systemic circulations. Cardiovascular disease includes heart disease, vascular diseases of the brain and kidney, and peripheral arterial diseases. Cardiovascular disease is the leading cause of death globally. Studies on cardiovascular regulation are important to provide a better understanding of this group of diseases and to help improve the corresponding treatment.
Ziele für Cardiovascular
Produkte für Cardiovascular
- Bestell-Nr. Artikelname Informationen
- GC48612 Propafenone-d5 (hydrochloride) An internal standard for the quantification of propafenone
-
GC47980
Propionyl-L-carnitine-d3 (chloride)
An internal standard for the quantification of propionyl-L-carnitine
-
GC18310
Prostaglandin A1
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen.
- GC18855 Prostaglandin A1 ethyl ester Prostaglandin A1 (PGA1) ethyl ester is a prodrug form of PGA1 with enhanced lipid solubility.
- GC40340 Prostaglandin A1 methyl ester Prostaglandin A1 (PGA1) has been shown to cause renal vasodilation, increase urine sodium excretion, and lowers arterial pressure in hypertensive patients.
- GC18353 Prostaglandin A2 A naturally occurring prostaglandin with antiviral/antitumor activity
-
GC18411
Prostaglandin B2
Prostaglandin B2 (PGB2) is a non-enzymatic dehydration product resulting from the treatment of PGE2 or PGA2 with strong base.
- GC18999 Prostaglandin D1 Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of DGLA, but to date it has not been isolated as a natural product.
- GC41170 Prostaglandin D2 methyl ester Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis.
- GC40610 Prostaglandin D3 Prostaglandin D3 (PGD3) is produced by the metabolism of EPA via the COX pathway.
- GC18768 Prostaglandin E1 ethyl ester Prostaglandin E1 (PGE1) is the theoretical cyclooxygenase metabolite of dihomo-γ-linolenic acid.
- GC44728 Prostaglandin I3 (sodium salt) PGI3 is synthesized from EPA by COX and PGI synthase.
- GC49873 Protectin D1 methyl ester An esterified form of protectin D1
- GP10053 Prothrombin (474-477) [Mus musculus]
- GC44732 Protopine (hydrochloride) Protopine is an alkaloid found in Berberidaceae, Ranunculaceae, Rutaceae, Fumariaceae, and Papaveraceae with diverse biological activities.
- GC48406 PSI (trifluoroacetate salt) A proteasome inhibitor
- GC48356 Psychotridine An alkaloid with diverse biological activities
- GC49424 Pyridostigmine-d3 (bromide) An internal standard for the quantification of pyridostigmine
- GC45903 Quazinone A PDE3 inhibitor
- GC48513 Quinapril-d5 An internal standard for the quantification of quinapril
- GC52034 Quinaprilat Quinaprilat ist ein oral wirksamer Nicht-Mercapto-Hemmer des Angiotensin Converting Enzyme (ACE), des aktiven Metaboliten von Quinapril.
- GC44799 Quinidine N-oxide Quinidine N-oxide is a pharmacologically inactive quinidine metabolite.
- GC45817 Quinidine-d3 An internal standard for the quantification of quinidine
- GC44801 R-(-)-Flecainide R-(-)-Flecainide is the (R) enantiomer of the antiarrhythmic agent flecainide.
- GC44803 rac-7-hydroxy Propranolol (hydrochloride) rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol).
- GC40967 rac-7-methoxy Propranolol Propranolol, one of the first β-blockers used in cardiovascular medicine, inhibits β1-, β2-, and β3-adrenergic receptors with log KD values of -8.16, -9.08, and -6.93, respectively.
- GC49291 rac-N-desmethyl Ivabradine-d6 (hydrochloride) An internal standard for the quantification of N-desmethyl ivabradine
- GC49108 Racecadotril-d5 An internal standard for the quantification of racecadotril
- GC49653 Ramipril Diketopiperazine A potential impurity found in commercial preparations of ramipril
- GC49408 Ramipril Diketopiperazine Acid A potential impurity found in commercial preparations of ramipril
- GC40234 Ramipril-d5 Ramipril-d5 is intended for use as an internal standard for the quantification of ramipril by GC- or LC-MS.
- GC40235 Ranolazine-d5 Ranolazine-d5 is intended for use as an internal standard for the quantification of ranolazine by GC- or LC-MS.
- GC48972 Resolvin E2 A specialized pro-resolving mediator
- GC48052 Rilmenidine-d4 An internal standard for the quantification of rilmenidine
- GC60326 Rivaroxaban D4 Rivaroxaban D4 (BAY 59-7939 D4) ist ein mit Deuterium gekennzeichnetes Rivaroxaban.
- GC49413 Rizatriptan N-oxide A potential impurity found in commercial preparations of rizatriptan
- GC48583 Rizatriptan-d6 (benzoate salt) An internal standard for the quantification of rizatriptan
- GC49107 Rosuvastatin lactone The lactone form of rosuvastatin
- GC48060 Rosuvastatin-d6 (sodium salt) An internal standard for the quantification of rosuvastatin
- GC49190 Roxadustat-d5 Roxadustat-d5 ist Deuterium mit der Bezeichnung Roxadustat. Roxadustat ist ein oraler Prolyl-Hydroxylase-Inhibitor (HIF-PHI), der den Faktor Hypoxie induzieren kann und der die Erythropoese fÖrdert, indem er das endogene Erythropoetin erhÖht, die Eisenregulierung verbessert und Hepcidin reduziert.
- GC44860 S1QEL1.1 S1QEL1.1 is a small molecule that suppresses superoxide production during reverse electron transport through the IQ site of the mitochondrial respiratory complex I (IC50 = 70 nM) without affecting oxidative phosphorylation.
- GC49093 Safflower Red A red pigment with diverse biological activities
- GC44868 Salbutamol (hydrochloride) Levalbuterol ((R)-Albuterol) Hydrochlorid ist ein kurzwirksamer β2-adrenerger Rezeptoragonist und das aktive (R)-Enantiomer von Salbutamol.
- GC45558 Salbutamol-d9
- GC49679 Sauvagine (trifluoroacetate salt) A neuropeptide hormone
-
GC49333
SH-42
Ein Hemmstoff von DHCR24
- GC49358 Sildenafil Chlorosulfonyl An intermediate in the synthesis of sildenafil
- GC48078 Sildenafil-d3 Sildenafil-d3 ist Deuterium mit der Bezeichnung Sildenafil-d3.
- GC50196 Simvastatin - d6 Deuterated simvastatin
- GC49002 Sinigrin (hydrate) Sinigrin (Hydrat) ist ein natürliches aliphatisches Glucosinolat, das in Pflanzen der Familie Brassicaceae vorkommt.
- GC44910 Sodium Hydrogen Sulfide (hydrate) Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals.
- GC49341 Spermidine-d6 An internal standard for the quantification of spermidine
- GC52390 Spexin 1 (human, mouse, rat, bovine) (acetate) An endogenous peptide and agonist of GAL2 and GAL3
- GC52233 SSPalmO-Phe An ionizable cationic self-degradable SSPalm
- GC52011 Stearic Acid glycidyl ester An esterified form of stearic acid
- GC49770 Stearic Acid glycidyl ester-d5 An internal standard for the quantification of stearic acid glycidyl ester
- GC52112 Stercobilinogen (technical grade) A metabolite of bilirubin and a precursor in the biosynthesis of stercobilin
- GC49500 Stobadine A pyridoindole antioxidant
- GC48117 Sumatriptan-d6 (succinate) An internal standard for the quantification of sumatriptan
- GC52125 T-1095 T-1095 ist ein selektiver und oral aktiver Inhibitor des Na+--Glucose-Cotransporters (SGLT) mit IC50-Werten von 22,8 μM und 2,3 μM fÜr humanes SGLT1 bzw. SGLT2.
- GC48121 Tadalafil-d3 An internal standard for the quantification of tadalafil
- GC52460 tcY-NH2 (trifluoroacetate salt) A peptide antagonist of PAR4
- GC45007 Telmisartan Acyl-β-D-Glucuronide Telmisartan acyl-β-D-glucuronide is a major metabolite of the angiotensin II receptor antagonist telmisartan.
- GC52478 Telmisartan Acyl-β-D-Glucuronide (hydrate) A major metabolite of telmisartan
- GC48137 Telmisartan-d3 An internal standard for the quantification of telmisartan
- GC18202 Temocaprilat An ACE inhibitor
- GC49386 Tepoxalin Tepoxalin ist ein dualer Inhibitor von COX und 5-Lipoxygenase (5-LO) mit starker entzÜndungshemmender Wirkung und einem gÜnstigen gastrointestinalen Profil.
- GC45017 Terpendole C Terpendol C, produziert von Albophoma yamanashiensis, zeigt eine starke inhibitorische AktivitÄt gegen Acyl-CoA: Cholesterin-Acyltransferase (ACAT).
- GC48162 Theobromine-d6 An internal standard for the quantification of theobromine
- GC48174 Thiorphan-d5 An internal standard for the quantification of thiorphan
- GP10085 Thrombin Receptor Activator for Peptide 5 (TRAP-5)
- GC45050 Thrombin Receptor Agonist Peptide (trifluoroacetate salt) Thrombin receptor agonist peptide (TRAP-14) is a 14-amino acid peptide agonist of the α-thrombin receptor.
- GC45051 Thrombin Receptor Peptide Ligand (trifluoroacetate salt) Thrombin receptor peptide ligand is antagonist of the thrombin receptor (EC50s = 16-33 μM to inhibit platelet aggregation in vitro).
- GC52254 Thrombin-Sensitive Peptide (ammonium acetate salt) A synthetic peptide containing a thrombin-releasable quencher
- GC48180 Ticagrelor-d7 An internal standard for the quantification of ticagrelor
- GC49076 Tilmicosin-d3 An internal standard for the quantification of tilmicosin
- GC49062 Tiopronin-d3 Tiopronin-d3 ist das mit Deuterium bezeichnete Tiopronin.
- GC45057 TIQ-A TIQ-A ist ein potenter TNKS (Poly-ART, PARP)-Inhibitor mit einem IC50-Wert von 24 nM fÜr TNKS2.
- GC19438 TMB 8 (hydrochloride) TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and α3β4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells.
- GC45060 TMP-153 Acyl-CoA:cholesterol acyltransferase (ACAT) catalyses the esterification of excess cellular cholesterol with fatty acids and is important for intestinal cholesterol absorption, hepatic lipoprotein secretion, and cholesterol accumulation in vascular tissues.
- GC48186 Tolvaptan-d7 Tolvaptan-D7 (OPC-41061-D7) ist das mit Deuterium gekennzeichnete Tolvaptan.
- GC48187 Torasemide-d7 An internal standard for the quantification of torasemide
- GC46233 Trandolaprilat (hydrate) Trandolaprilat (Hydrat) ist ein starker Hemmer des Angiotensin-Converting-Enzyms (ACE).
- GC52436 TRAP-6 amide (trifluoroacetate salt) A peptide PAR1 agonist
- GC45073 TRAP-6 Peptide (trifluoroacetate salt) TRAP-6 peptide is a hexapeptide corresponding to residues 42-47 of protease-activated receptor 1 (PAR1).
- GC48202 Treprostinil (diethanolamine salt) Treprostinil (UT-15C) Diethanolamin ist ein potenter EP2-, DP1- und IP-Agonist mit Ki-Werten von 3,6, 4,4, 32,1, 212, 826, 2505 und 4680 nM fÜr EP2, DP1, IP, EP1, EP4, EP3 bzw. FP .
- GC49141 Triacontanoic Acid A very long-chain saturated fatty acid
- GC52005 Triazolomethylindole-3-acetic Acid A metabolite of rizatriptan
- GC49072 Tribenoside Tribenosid ist ein vasoprotektives Mittel, das fÜr die Erforschung von HÄmorrhoiden verwendet werden kann.
- GC49884 Trigonelline-d3 (chloride) An internal standard for the quantification of trigonelline
- GC48206 Trimethylamine-d9 N-oxide An internal standard for the quantification of trimethylamine N-oxide
- GC45090 Triparanol Triparanol is a 24-dehydro cholesterol reductase (DHCR24) inhibitor (Ki = 0.523 μM), which is an enzyme involved in the biosynthesis of cholesterol.
- GC49389 Tritylolmesartan Medoxomil An intermediate in the synthesis of olmesartan medoxomil
- GC45096 Tyr-α-CGRP (human) (trifluoroacetate salt) Tyr-α-CGRP is an N-terminal extended tyrosinated analogue of α-calcitonin gene-related peptide.
- GC18962 U-92016A U-92016A ist ein potenter, metabolisch stabiler, oral aktiver 5-HT1A-Rezeptoragonist mit einem außergewÖhnlich hohen Grad an intrinsischer AktivitÄt.
- GC49328 UDP-α-D-Galactose (sodium salt) A nucleotide sugar
- GC45126 Uric Acid (sodium salt) HarnsÄure (Natriumsalz) (Mononatriumurat), FÄnger von Sauerstoffradikalen, ist ein sehr wichtiges Antioxidans, das hilft, die StabilitÄt des Blutdrucks und antioxidativen Stress aufrechtzuerhalten.
- GC49812 Urobilin (hydrochloride) A byproduct of hemoglobin degradation
- GC18231 Urocortin II (human) (trifluoroacetate salt) Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I.
- GC45130 Urodilatin Urodilatin is a renal natriuretic peptide first isolated from human urine.