Cardiovascular

13,14-dihydro Prostaglandin E1 (13,14-dihydro PGE1) is a biologically active metabolite of PGE1 with comparable potency to the parent compound.

Carbazeran, ein potenter Phosphodiesterase-Hemmer, ist ein Aldehyd-Oxidase-Substrat.

PAF C-18:1 is a naturally occurring phospholipid produced by cells upon stimulation and plays a role in the establishment and maintenance of the inflammatory response.

Luteoloside is a flavonoid that has been found in many Chinese herbs with diverse biological activities.

5-hydroxy Propranolol is a metabolite of propranolol, a β-adrenergic receptor antagonist.

Digitoxigenin is a cardenolide and aglycone constituent of digitoxin, an extract from the foxglove plant, D.

Palmitoleic acid is a common constituent of the triglycerides of human adipose tissue.

Matairesinol verleiht einem allergischen Dermatitis-Mausmodell antiallergische Wirkungen.

24-Dehydrocholesterin ist ein Molekül, das Cholesterin ähnelt.

The early stage of atherosclerosis is characterized by the aggregation of foam cells, so called a fatty streak, in the inner arterial wall.

Methyldopat ist ein Ethylester-Prodrug von α-Methyldopa

(±)13-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.

Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes.

(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively).

(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol, which is a metabolite of propranolol.

Arachidonoyl ethanolamide (AEA; anandamide) is an endogenous lipid neurotransmitter with cannabinergic activity, binding to both the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.

(±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.

(3S)-hydroxy Quinidine is an active quinidine metabolite.

(Ala1)-PAR4 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse PAR4 and residues 60-65 of the full-length sequence with an alanine residue substituted for glycine at position 1/60.

(Ala1)-PAR4 (1-6) amide (mouse) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that induces aggregation of rat and human platelets in vitro (EC50s = 15 and 60 μM, respectively).

The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids: apelin-36, apelin-17, and apelin-13, respectively.

(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide.

1,3,7-TrimethylursÄure ist der Metabolit von Koffein. Das metabolische VerhÄltnis von 1,3,7-TrimethylursÄure zu Koffein kann als Biomarker zur Beschreibung der VariabilitÄt der CYP3A-AktivitÄt in einer Kohorte ausgewertet werden.

1,3-Dioctanoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains octanoic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position.