GLPBio

DSP-4

Catalog No.: GC12042Purity:>98.00%Synonyms: Neurotoxin DSP 4 hydrochloride
COASDSData Sheet
DSP-4 is a highly and selective adrenergic neurotoxin.

Products are for research use only. Not for human use. We do not sell to patients.

DSP-4
Cas No.: 40616-75-9
10mM (in 1mL DMSO)In Stock
$55.00
1
5mgIn Stock
$57.00
1
10mgIn Stock
$94.00
1
50mgIn Stock
$178.00
1
100mgIn Stock
$277.00
1
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Citations

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Description

DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats, can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC)[1][2].

References:
[1]. Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41.
[2]. Jaim-Etcheverry G, et al. DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats. Brain Res. 1980 Apr 28;188(2):513-23.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
40616-75-9
Synonyms
Neurotoxin DSP 4 hydrochloride
Chemical Name
N-(2-bromobenzyl)-2-chloro-N-ethylethanamine hydrochloride
SMILES
BrC1=CC=CC=C1CN(CC)CCCl.Cl
Molecular Formula
C11H15BrClN.HCl
Molecular Weight
313.06
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml
Storage
Desiccate at RT
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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