Polymyxin B1 Isoleucine |
| Catalog No.GC41386 |
The polymyxins are cationic peptides originally isolated from B.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 80469-10-9
Sample solution is provided at 25 µL, 10mM.
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The polymyxins are cationic peptides originally isolated from B. polymyxa. They bind and kill Gram-negative bacteria. The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B1 Isoleucine differs from polymyxin B1 by having isoleucine rather than leucine as a component of the cyclic peptide. Polymyxin B1 isoleucine is comparable to other B polymyxins in its ability to kill P. aeruginosa, A. baumannii, and K. pneumoniae isolates. Its relative pharmacokinetics and nephrotoxicity have not been examined.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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