FK-409 (Synonyms: NOR-3) |
| Catalog No.GC43669 |
FK-409 is a NO donor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 138472-01-2
Sample solution is provided at 25 µL, 10mM.
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FK-409 is a NO donor. It liberates NO in a time-dependent manner with a half-life of approximately 40 minutes in phosphate buffer (pH 7.4) at 37°C. [1] The IC50 for the inhibition of platelet aggregation is 4.9 µM. [2]
Reference:
[1]. Kita, Y., Hirasawa, Y., Maeda, K., et al. Spontaneous nitric oxide release accounts for the potent pharmacological actions of FK409. European Journal of Pharmacology 257, 123-130 (1994).
[2]. Fukuyama, S., Hirasawa, Y., Kato, Y., et al. Structure-activity relationships of spontaneous nitric oxide releasers, FK409 and its derivatives. Journal of Pharmacology and Experimental Therapeutics 282, 236-242 (1997).
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
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